A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction Settings
Aims: For patients prescribed methadone wishing to access buprenorphine ORT, the current practice is to reduce the methadone dose to 30/40 ml and cessation of methadone for 48 hrs prior to the switch. This exposes these patients to risk of psychological, physical distress or relapse into non-prescri...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2025-06-01
|
| Series: | BJPsych Open |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2056472425107722/type/journal_article |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849708942859436032 |
|---|---|
| author | Zelda Summers Jennie Rankine Stuart Fisher |
| author_facet | Zelda Summers Jennie Rankine Stuart Fisher |
| author_sort | Zelda Summers |
| collection | DOAJ |
| description | Aims: For patients prescribed methadone wishing to access buprenorphine ORT, the current practice is to reduce the methadone dose to 30/40 ml and cessation of methadone for 48 hrs prior to the switch. This exposes these patients to risk of psychological, physical distress or relapse into non-prescribed opiate use. |
| format | Article |
| id | doaj-art-aeeccd0fe08d42b5991f3887dc707d67 |
| institution | DOAJ |
| issn | 2056-4724 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | BJPsych Open |
| spelling | doaj-art-aeeccd0fe08d42b5991f3887dc707d672025-08-20T03:15:29ZengCambridge University PressBJPsych Open2056-47242025-06-0111S320S32110.1192/bjo.2025.10772A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction SettingsZelda SummersJennie RankineStuart Fisher0Cardiff and Vale University Health Board, Cardiff, United KingdomAims: For patients prescribed methadone wishing to access buprenorphine ORT, the current practice is to reduce the methadone dose to 30/40 ml and cessation of methadone for 48 hrs prior to the switch. This exposes these patients to risk of psychological, physical distress or relapse into non-prescribed opiate use.https://www.cambridge.org/core/product/identifier/S2056472425107722/type/journal_article |
| spellingShingle | Zelda Summers Jennie Rankine Stuart Fisher A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction Settings BJPsych Open |
| title | A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction Settings |
| title_full | A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction Settings |
| title_fullStr | A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction Settings |
| title_full_unstemmed | A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction Settings |
| title_short | A Case Series Demonstrating the Feasibility of Microdosing as a Bridging Method to Enable a Comfortable and Effective Transition From Prescribed Methadone to Buprenorphine ORT (Opiate Replacement Therapy), Without Initial Methadone Dose Reduction or Cessation, in UK Community Addiction Settings |
| title_sort | case series demonstrating the feasibility of microdosing as a bridging method to enable a comfortable and effective transition from prescribed methadone to buprenorphine ort opiate replacement therapy without initial methadone dose reduction or cessation in uk community addiction settings |
| url | https://www.cambridge.org/core/product/identifier/S2056472425107722/type/journal_article |
| work_keys_str_mv | AT zeldasummers acaseseriesdemonstratingthefeasibilityofmicrodosingasabridgingmethodtoenableacomfortableandeffectivetransitionfromprescribedmethadonetobuprenorphineortopiatereplacementtherapywithoutinitialmethadonedosereductionorcessationinukcommunityaddictionsettings AT jennierankine acaseseriesdemonstratingthefeasibilityofmicrodosingasabridgingmethodtoenableacomfortableandeffectivetransitionfromprescribedmethadonetobuprenorphineortopiatereplacementtherapywithoutinitialmethadonedosereductionorcessationinukcommunityaddictionsettings AT stuartfisher acaseseriesdemonstratingthefeasibilityofmicrodosingasabridgingmethodtoenableacomfortableandeffectivetransitionfromprescribedmethadonetobuprenorphineortopiatereplacementtherapywithoutinitialmethadonedosereductionorcessationinukcommunityaddictionsettings AT zeldasummers caseseriesdemonstratingthefeasibilityofmicrodosingasabridgingmethodtoenableacomfortableandeffectivetransitionfromprescribedmethadonetobuprenorphineortopiatereplacementtherapywithoutinitialmethadonedosereductionorcessationinukcommunityaddictionsettings AT jennierankine caseseriesdemonstratingthefeasibilityofmicrodosingasabridgingmethodtoenableacomfortableandeffectivetransitionfromprescribedmethadonetobuprenorphineortopiatereplacementtherapywithoutinitialmethadonedosereductionorcessationinukcommunityaddictionsettings AT stuartfisher caseseriesdemonstratingthefeasibilityofmicrodosingasabridgingmethodtoenableacomfortableandeffectivetransitionfromprescribedmethadonetobuprenorphineortopiatereplacementtherapywithoutinitialmethadonedosereductionorcessationinukcommunityaddictionsettings |