Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement
Background. Dental implant therapy is a top option for replacing lost or unsalvageable teeth. The most common placement protocols are immediate and delayed. A key factor for successful treatment is the stability of the marginal bone, which can be evaluated through radiography and salivary biomarkers...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2025-03-01
|
| Series: | Journal of Advanced Periodontology and Implant Dentistry |
| Subjects: | |
| Online Access: | https://japid.tbzmed.ac.ir/PDF/japid-17-40.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849738368795017216 |
|---|---|
| author | Bahareh Hekmat Masoumeh Amani Farhad Aghmasheh Zahra Mohammad Hasani |
| author_facet | Bahareh Hekmat Masoumeh Amani Farhad Aghmasheh Zahra Mohammad Hasani |
| author_sort | Bahareh Hekmat |
| collection | DOAJ |
| description | Background. Dental implant therapy is a top option for replacing lost or unsalvageable teeth. The most common placement protocols are immediate and delayed. A key factor for successful treatment is the stability of the marginal bone, which can be evaluated through radiography and salivary biomarkers. This study evaluated the relationship between salivary alkaline phosphatase levels and the alveolar crest bone height in immediate and delayed implants. Methods. This study involved 62 patients: 31 for immediate and 31 for delayed implant placement in posterior jaw regions. Unstimulated saliva (5 mL) was collected from all the patients before surgery and at 14- and 4-month postoperative intervals to assess salivary alkaline phosphatase activity using spectrophotometry. Intraoral periapical digital radiographs were taken immediately after surgery and 2 and 4 months postoperatively to evaluate alveolar crest bone height. Measurements at the mesial and distal implant sites were analyzed using Scanora software. Results. No significant differences were found in salivary alkaline phosphatase activity or alveolar crest bone resorption based on gender, implant timing, or jaw region (P>0.05). However, patient age significantly correlated with alkaline phosphatase activity and bone resorption (P<0.05). There was no correlation between alkaline phosphatase levels and alveolar crest bone height. Conclusion. Salivary alkaline phosphatase cannot be considered a reliable diagnostic biomarker for evaluating the condition of the alveolar crest bone around dental implants. |
| format | Article |
| id | doaj-art-aeea17f565a64f1e8ab82918b8b71ada |
| institution | DOAJ |
| issn | 2645-5390 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Periodontology and Implant Dentistry |
| spelling | doaj-art-aeea17f565a64f1e8ab82918b8b71ada2025-08-20T03:06:36ZengTabriz University of Medical SciencesJournal of Advanced Periodontology and Implant Dentistry2645-53902025-03-01171404510.34172/japid.2025.006japid-3684Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placementBahareh Hekmat0Masoumeh Amani1Farhad Aghmasheh2Zahra Mohammad Hasani3Department of Oral and Maxillofacial Radiology, School of Dentistry, Zanjan University of Medical Sciences, Zanjan, IranDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Zanjan University of Medical Sciences, Zanjan, IranDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Zanjan University of Medical Sciences, Zanjan, IranDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Zanjan University of Medical Sciences, Zanjan, IranBackground. Dental implant therapy is a top option for replacing lost or unsalvageable teeth. The most common placement protocols are immediate and delayed. A key factor for successful treatment is the stability of the marginal bone, which can be evaluated through radiography and salivary biomarkers. This study evaluated the relationship between salivary alkaline phosphatase levels and the alveolar crest bone height in immediate and delayed implants. Methods. This study involved 62 patients: 31 for immediate and 31 for delayed implant placement in posterior jaw regions. Unstimulated saliva (5 mL) was collected from all the patients before surgery and at 14- and 4-month postoperative intervals to assess salivary alkaline phosphatase activity using spectrophotometry. Intraoral periapical digital radiographs were taken immediately after surgery and 2 and 4 months postoperatively to evaluate alveolar crest bone height. Measurements at the mesial and distal implant sites were analyzed using Scanora software. Results. No significant differences were found in salivary alkaline phosphatase activity or alveolar crest bone resorption based on gender, implant timing, or jaw region (P>0.05). However, patient age significantly correlated with alkaline phosphatase activity and bone resorption (P<0.05). There was no correlation between alkaline phosphatase levels and alveolar crest bone height. Conclusion. Salivary alkaline phosphatase cannot be considered a reliable diagnostic biomarker for evaluating the condition of the alveolar crest bone around dental implants.https://japid.tbzmed.ac.ir/PDF/japid-17-40.pdfalkaline phosphatasealveolar bonebone metabolismimmediate implantsalivary biomarkers |
| spellingShingle | Bahareh Hekmat Masoumeh Amani Farhad Aghmasheh Zahra Mohammad Hasani Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement Journal of Advanced Periodontology and Implant Dentistry alkaline phosphatase alveolar bone bone metabolism immediate implant salivary biomarkers |
| title | Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement |
| title_full | Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement |
| title_fullStr | Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement |
| title_full_unstemmed | Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement |
| title_short | Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement |
| title_sort | salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs delayed implant placement |
| topic | alkaline phosphatase alveolar bone bone metabolism immediate implant salivary biomarkers |
| url | https://japid.tbzmed.ac.ir/PDF/japid-17-40.pdf |
| work_keys_str_mv | AT baharehhekmat salivaryalkalinephosphataselevelsandalveolarbonecrestchangesinimmediatevsdelayedimplantplacement AT masoumehamani salivaryalkalinephosphataselevelsandalveolarbonecrestchangesinimmediatevsdelayedimplantplacement AT farhadaghmasheh salivaryalkalinephosphataselevelsandalveolarbonecrestchangesinimmediatevsdelayedimplantplacement AT zahramohammadhasani salivaryalkalinephosphataselevelsandalveolarbonecrestchangesinimmediatevsdelayedimplantplacement |