Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus
Uremia is the advanced stage of chronic kidney disease (CKD), characterized by the accumulation of metabolic waste products in the blood as a result of the kidneys' inability to meet the body's metabolic demands. Patients with uremia frequently experience a range of complications, includin...
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2025.1529183/full |
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| author | Ying Li Yaohua Chen Jingyi Nie Xiaoguang Huang Weiwei Zhang |
| author_facet | Ying Li Yaohua Chen Jingyi Nie Xiaoguang Huang Weiwei Zhang |
| author_sort | Ying Li |
| collection | DOAJ |
| description | Uremia is the advanced stage of chronic kidney disease (CKD), characterized by the accumulation of metabolic waste products in the blood as a result of the kidneys' inability to meet the body's metabolic demands. Patients with uremia frequently experience a range of complications, including renal anemia, osteoporosis, and cardiovascular disease, all of which significantly impair their quality of life. Chronic kidney disease-associated pruritus (CKD-aP) is a common comorbidity in uremic patients, particularly among those undergoing hemodialysis, with prevalence rates ranging from 10 to 77%. This case report enrolled three patients diagnosed with chronic kidney disease-associated pruritus (CKD-ap) who underwent ultrasound-guided sympathetic nerve blockade procedures. The results demonstrated significant reductions in pruritus intensity concurrent with measurable enhancements in sleep quality and daily functioning. |
| format | Article |
| id | doaj-art-aee43340cce54c869845efd079afe27f |
| institution | DOAJ |
| issn | 1662-453X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj-art-aee43340cce54c869845efd079afe27f2025-08-20T03:10:18ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2025-04-011910.3389/fnins.2025.15291831529183Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritusYing Li0Yaohua Chen1Jingyi Nie2Xiaoguang Huang3Weiwei Zhang4Department of Anesthesiology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, ChinaDepartment of Anesthesiology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, ChinaDepartment of Anesthesiology, Shanxi Medical University, Taiyuan, ChinaDepartment of Nephrology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, ChinaDepartment of Anesthesiology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, ChinaUremia is the advanced stage of chronic kidney disease (CKD), characterized by the accumulation of metabolic waste products in the blood as a result of the kidneys' inability to meet the body's metabolic demands. Patients with uremia frequently experience a range of complications, including renal anemia, osteoporosis, and cardiovascular disease, all of which significantly impair their quality of life. Chronic kidney disease-associated pruritus (CKD-aP) is a common comorbidity in uremic patients, particularly among those undergoing hemodialysis, with prevalence rates ranging from 10 to 77%. This case report enrolled three patients diagnosed with chronic kidney disease-associated pruritus (CKD-ap) who underwent ultrasound-guided sympathetic nerve blockade procedures. The results demonstrated significant reductions in pruritus intensity concurrent with measurable enhancements in sleep quality and daily functioning.https://www.frontiersin.org/articles/10.3389/fnins.2025.1529183/fullCKD-aPuremiasympathetic nerve blockchronic kidney diseaseautonomic nervous system |
| spellingShingle | Ying Li Yaohua Chen Jingyi Nie Xiaoguang Huang Weiwei Zhang Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus Frontiers in Neuroscience CKD-aP uremia sympathetic nerve block chronic kidney disease autonomic nervous system |
| title | Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus |
| title_full | Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus |
| title_fullStr | Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus |
| title_full_unstemmed | Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus |
| title_short | Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus |
| title_sort | case report sympathetic nerve block treat chronic kidney disease associated pruritus |
| topic | CKD-aP uremia sympathetic nerve block chronic kidney disease autonomic nervous system |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2025.1529183/full |
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