Genome-wide CRISPR/Cas9 screen reveals factors that influence the susceptibility of tumor cells to NK cell-mediated killing

Genome-wide CRISPR/Cas9 screen reveals factors that influence the susceptibility of tumor cells to NK cell-mediated killing

Background Natural killer (NK) cells exhibit potent cytotoxic activity against various cancer cell types. Over the past five decades, numerous methodologies have been employed to elucidate the intricate molecular mechanisms underlying NK cell-mediated tumor control. While significant progress has be...

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Main Authors: Eric Vivier, Benjamin Rossi, Laurent Gauthier, Emilie Narni-Mancinelli, Justine Galluso, Sophie Guia, Aurore Fenis, Camille Baudesson De Chanville, Hakim Medjouel, Bertrand Escaliere, Angelika Modelska, Margaux Vienne, Noella Lopes, Amelie Pouchin, Sandrine Roulland
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/3/e010699.full
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