Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T wave

The assessment of reperfusion effectiveness in acute myocardial infarction (AMI) is an important clinical task. In 106 AMI patients with ST elevation, the dynamics of ST segment and Twave was analyzed using the data of three electrocardiograms (baseline, 3 and 48 hours after thrombolysis - ECG-1, 2,...

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Main Author: L. L. Berstein
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2007-12-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/2247
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author L. L. Berstein
author_facet L. L. Berstein
author_sort L. L. Berstein
collection DOAJ
description The assessment of reperfusion effectiveness in acute myocardial infarction (AMI) is an important clinical task. In 106 AMI patients with ST elevation, the dynamics of ST segment and Twave was analyzed using the data of three electrocardiograms (baseline, 3 and 48 hours after thrombolysis - ECG-1, 2, and 3, respectively). Separately for anterior and поп-anterior AMI, ST decrease degree in the lead with its maximal elevation (STmax decrease aAMI, naAMI), as well as decrease in total ST elevation in all leads with its elevation (STsum decrease aAMI, naAMI) were analyzed. Other parameters calculated included summary T wave amplitudes in leads with ST elevation on ECG-2 and ECG-3 (sumT2, sumT3), their difference between ECG-2 and ECG-3 (sumT2-sumT1) or between ECG-3 and ECG-1 (sumT3-sumT1). Reperfusion effectiveness was assessed by local left ventricular contractility index reduction 10±3 days after thrombolysis. Sensitivity and specificity of these criteria, with calculated cut-off levels, were as follows: sumT3-sumTl?28*: 68 and 76 %; STsum decrease aAMI >44, 0 % - 81 and 62 %; STsum decrease naAMI >58, 8 %* - 100 and 42 %; STmax decrease naAMI>66, 7 %* - 83 and 53 %; STmax decrease aAMI>33, 3 %* - 81 and 54 %; sumT3<10* - 98 and 30 %; sumT2-sumT1?28* - 39 and 86 %; sumT2<14 -75 and 43 % (*p<0, 05). Analyzing simple electrocardiography parameters could facilitate the assessment of myocardial reperfusion effectiveness in AMI.
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spelling doaj-art-aed9cd3380f5435ab9ba9c41cd1e79a52025-08-20T03:57:25Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-12-010637411999Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T waveL. L. Berstein0Медицинская академия последипломного образованияThe assessment of reperfusion effectiveness in acute myocardial infarction (AMI) is an important clinical task. In 106 AMI patients with ST elevation, the dynamics of ST segment and Twave was analyzed using the data of three electrocardiograms (baseline, 3 and 48 hours after thrombolysis - ECG-1, 2, and 3, respectively). Separately for anterior and поп-anterior AMI, ST decrease degree in the lead with its maximal elevation (STmax decrease aAMI, naAMI), as well as decrease in total ST elevation in all leads with its elevation (STsum decrease aAMI, naAMI) were analyzed. Other parameters calculated included summary T wave amplitudes in leads with ST elevation on ECG-2 and ECG-3 (sumT2, sumT3), their difference between ECG-2 and ECG-3 (sumT2-sumT1) or between ECG-3 and ECG-1 (sumT3-sumT1). Reperfusion effectiveness was assessed by local left ventricular contractility index reduction 10±3 days after thrombolysis. Sensitivity and specificity of these criteria, with calculated cut-off levels, were as follows: sumT3-sumTl?28*: 68 and 76 %; STsum decrease aAMI >44, 0 % - 81 and 62 %; STsum decrease naAMI >58, 8 %* - 100 and 42 %; STmax decrease naAMI>66, 7 %* - 83 and 53 %; STmax decrease aAMI>33, 3 %* - 81 and 54 %; sumT3<10* - 98 and 30 %; sumT2-sumT1?28* - 39 and 86 %; sumT2<14 -75 and 43 % (*p<0, 05). Analyzing simple electrocardiography parameters could facilitate the assessment of myocardial reperfusion effectiveness in AMI.https://russjcardiol.elpub.ru/jour/article/view/2247acute myocardial infarctionthrombolytic therapyreperfusion effectivenessassessment
spellingShingle L. L. Berstein
Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T wave
Российский кардиологический журнал
acute myocardial infarction
thrombolytic therapy
reperfusion effectiveness
assessment
title Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T wave
title_full Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T wave
title_fullStr Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T wave
title_full_unstemmed Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T wave
title_short Non-invasive assessment of thrombolysis results in acute myocardial infarction: electrocardiogram dynamics of ST segment elevation and T wave
title_sort non invasive assessment of thrombolysis results in acute myocardial infarction electrocardiogram dynamics of st segment elevation and t wave
topic acute myocardial infarction
thrombolytic therapy
reperfusion effectiveness
assessment
url https://russjcardiol.elpub.ru/jour/article/view/2247
work_keys_str_mv AT llberstein noninvasiveassessmentofthrombolysisresultsinacutemyocardialinfarctionelectrocardiogramdynamicsofstsegmentelevationandtwave