ASAP1 Promotes Epithelial to Mesenchymal Transition by Activating the TGFβ Pathway in Papillary Thyroid Cancer

ASAP1 Promotes Epithelial to Mesenchymal Transition by Activating the TGFβ Pathway in Papillary Thyroid Cancer

ABSTRACT Background Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy. While the prognosis of PTC is generally favorable, some cases exhibit aggressive behavior, leading to metastasis and recurrence. ASAP1 (ArfGAP with SH3, ankyrin repeats, and PH domain 1), an ADP‐ribosyl...

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Bibliographic Details
Main Authors: Shiji Song, Zixing Leng, Xinxin Zhao, Ziping Liu, Yongshuai Li, Wenjing Zhang, Junming Yue, Yuxia Fan
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Medicine
Subjects:
ASAP1
EMT
interaction
invasion
PTC
TGFβ
Online Access:https://doi.org/10.1002/cam4.71075
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