Hypomethylation induced overexpression of PLOD3 facilitates colorectal cancer progression through TM9SF4-mediated autophagy

Hypomethylation induced overexpression of PLOD3 facilitates colorectal cancer progression through TM9SF4-mediated autophagy

Abstract Colorectal cancer (CRC) ranks among the primary causes of human mortality globally. Numerous studies have highlighted the significant role of PLOD3 in the progression of various cancers. However, the exact function and underlying mechanisms of PLOD3 in CRC remains incompletely understood. T...

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Bibliographic Details
Main Authors: Renzhong Zhu, Chuanxin Tian, Nan Gao, Zhiqiang Li, Sheng Yang, Yue Zhang, Ming Zhou, Kangpeng Jin, Chuan Zhang, Yueming Sun
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07503-5
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