Kinome-wide CRISPR-Cas9 screens revealed EXOSC10 as a positive regulator of TGF-β signaling

Kinome-wide CRISPR-Cas9 screens revealed EXOSC10 as a positive regulator of TGF-β signaling

The TGF-β signaling pathway is closely associated with human health and disease, and the systematic identification of factors involved in the TGF-β signaling pathway significantly contributes to the understanding and treatment of various diseases. Through kinome-wide CRISPR screen, we identified 13...

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Bibliographic Details
Main Authors: Dingding Wang, Xinhao Zhang, Jianxun Guo, Weijia Liu, Yanchi Zhou, Renxian Wang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
TGF-β signaling
EXOSC10
Kinome-wide CRISPR screen
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580824002280
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