Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns

Purpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchan...

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Main Authors: Ágata Mota, Sofia Fonseca, Ângela Carneiro, Augusto Magalhães, Elisete Brandão, Fernando Falcão-Reis
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2012/864958
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author Ágata Mota
Sofia Fonseca
Ângela Carneiro
Augusto Magalhães
Elisete Brandão
Fernando Falcão-Reis
author_facet Ágata Mota
Sofia Fonseca
Ângela Carneiro
Augusto Magalhães
Elisete Brandão
Fernando Falcão-Reis
author_sort Ágata Mota
collection DOAJ
description Purpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchanged for years. Results. In the first case, spectral-domain optical coherence tomography (SD-OCT) showed reduced foveal pit and continuity of inner retinal layers in the fovea. Photoreceptor layer had a normal thickness centrally. The foveal avascular zone (FAZ) was absent in the flourescein angiogram (FA). Fundus autofluorescence showed reduced foveal attenuation of autofluorescence. In the second patient, there was the same pattern in SD-OCT, with normal aspect in FA and only a slightly reduced foveal attenuation of autofluorescence. Conclusion. OCT, as a noninvasive and quick method, is helpful in the diagnosis of foveal hypoplasia. FA and fundus autofluorescence were less sensitive.
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publishDate 2012-01-01
publisher Wiley
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-aec59eb93f5741a1a76c6070b434b0d82025-08-20T02:19:06ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302012-01-01201210.1155/2012/864958864958Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence PatternsÁgata Mota0Sofia Fonseca1Ângela Carneiro2Augusto Magalhães3Elisete Brandão4Fernando Falcão-Reis5Department of Ophthalmology, Hospital S. João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, PortugalDepartment of Ophthalmology, Hospital Vila Nova de Gaia/Espinho, Rua Conceição Fernandes, 4434-502 Vila Nova de Gaia, PortugalDepartment of Ophthalmology, Hospital S. João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, PortugalDepartment of Ophthalmology, Hospital S. João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, PortugalDepartment of Ophthalmology, Hospital S. João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, PortugalDepartment of Ophthalmology, Hospital S. João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, PortugalPurpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchanged for years. Results. In the first case, spectral-domain optical coherence tomography (SD-OCT) showed reduced foveal pit and continuity of inner retinal layers in the fovea. Photoreceptor layer had a normal thickness centrally. The foveal avascular zone (FAZ) was absent in the flourescein angiogram (FA). Fundus autofluorescence showed reduced foveal attenuation of autofluorescence. In the second patient, there was the same pattern in SD-OCT, with normal aspect in FA and only a slightly reduced foveal attenuation of autofluorescence. Conclusion. OCT, as a noninvasive and quick method, is helpful in the diagnosis of foveal hypoplasia. FA and fundus autofluorescence were less sensitive.http://dx.doi.org/10.1155/2012/864958
spellingShingle Ágata Mota
Sofia Fonseca
Ângela Carneiro
Augusto Magalhães
Elisete Brandão
Fernando Falcão-Reis
Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns
Case Reports in Ophthalmological Medicine
title Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns
title_full Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns
title_fullStr Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns
title_full_unstemmed Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns
title_short Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns
title_sort isolated foveal hypoplasia tomographic angiographic and autofluorescence patterns
url http://dx.doi.org/10.1155/2012/864958
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