Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot study

Objective Patients with advanced chronic kidney disease (CKD) face challenging decisions about kidney replacement therapy (KRT) options. This study aimed to evaluate the effectiveness of an Interactive Patient-Decision-Aid App for Kidney Replacement Therapy (iPtDA-KRT App) in improving decision self...

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Main Authors: Jun-Ming Su, Huey-Liang Kuo, Kai-Ling Yang, Chih-Jung Wu, Ya-Fang Ho
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Digital Health
Online Access:https://doi.org/10.1177/20552076251332832
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author Jun-Ming Su
Huey-Liang Kuo
Kai-Ling Yang
Chih-Jung Wu
Ya-Fang Ho
author_facet Jun-Ming Su
Huey-Liang Kuo
Kai-Ling Yang
Chih-Jung Wu
Ya-Fang Ho
author_sort Jun-Ming Su
collection DOAJ
description Objective Patients with advanced chronic kidney disease (CKD) face challenging decisions about kidney replacement therapy (KRT) options. This study aimed to evaluate the effectiveness of an Interactive Patient-Decision-Aid App for Kidney Replacement Therapy (iPtDA-KRT App) in improving decision self-efficacy, knowledge, and readiness while reducing decisional conflict and regret among patients with advanced CKD. Methods A prospective, two-arm clinical trial was conducted with 70 patients who used either the mobile app-based iPtDA-KRT or a paper-based PtDA for 4 weeks. Key measures included decision self-efficacy (DSES), decisional conflict (DCS), KRT knowledge (KRTKS), preparation for decision-making (PrepDM), and decision regret (DRS). These measures were assessed immediately post-intervention and at 4 weeks post-intervention. Additionally, outcomes such as DSES, DCS, and DRS were tracked at 8 weeks post-intervention. Data were analyzed using generalized estimating equations. Results The experimental group included 19 male and 16 female patients with a mean age of 66.4 ± 14.0 years, while the control group included 22 male and 13 female patients with a mean age of 59.7 ± 16.1 years. The experimental group demonstrated significantly greater and sustained improvements in self-efficacy, knowledge, and preparation for decision-making compared to the control group. Reductions in decisional conflict and regret were also maintained over time. Conclusions The iPtDA-KRT App demonstrated substantial and lasting benefits over paper-based PtDAs in supporting patients’ complex decision-making. These findings suggest that digital, interactive PtDAs may enhance informed decision-making, reduce long-term decisional conflict, and improve patient confidence in clinical settings. Trial Registration This study was registered at ClinicalTrials.gov (Identifier: NCT05666544).
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spelling doaj-art-aebf6a335b2d4f9ebf1c5dbc2ecea0902025-08-20T03:03:46ZengSAGE PublishingDigital Health2055-20762025-04-011110.1177/20552076251332832Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot studyJun-Ming Su0Huey-Liang Kuo1Kai-Ling Yang2Chih-Jung Wu3Ya-Fang Ho4 Department of Information and Learning Technology, National University of Tainan, Tainan City, Taiwan School of Medicine, China Medical University, Taichung, Taiwan Nephrology Medicine, , Taichung, Taiwan Department of Nursing, , Taichung, Taiwan Department of Nursing, , Taichung, TaiwanObjective Patients with advanced chronic kidney disease (CKD) face challenging decisions about kidney replacement therapy (KRT) options. This study aimed to evaluate the effectiveness of an Interactive Patient-Decision-Aid App for Kidney Replacement Therapy (iPtDA-KRT App) in improving decision self-efficacy, knowledge, and readiness while reducing decisional conflict and regret among patients with advanced CKD. Methods A prospective, two-arm clinical trial was conducted with 70 patients who used either the mobile app-based iPtDA-KRT or a paper-based PtDA for 4 weeks. Key measures included decision self-efficacy (DSES), decisional conflict (DCS), KRT knowledge (KRTKS), preparation for decision-making (PrepDM), and decision regret (DRS). These measures were assessed immediately post-intervention and at 4 weeks post-intervention. Additionally, outcomes such as DSES, DCS, and DRS were tracked at 8 weeks post-intervention. Data were analyzed using generalized estimating equations. Results The experimental group included 19 male and 16 female patients with a mean age of 66.4 ± 14.0 years, while the control group included 22 male and 13 female patients with a mean age of 59.7 ± 16.1 years. The experimental group demonstrated significantly greater and sustained improvements in self-efficacy, knowledge, and preparation for decision-making compared to the control group. Reductions in decisional conflict and regret were also maintained over time. Conclusions The iPtDA-KRT App demonstrated substantial and lasting benefits over paper-based PtDAs in supporting patients’ complex decision-making. These findings suggest that digital, interactive PtDAs may enhance informed decision-making, reduce long-term decisional conflict, and improve patient confidence in clinical settings. Trial Registration This study was registered at ClinicalTrials.gov (Identifier: NCT05666544).https://doi.org/10.1177/20552076251332832
spellingShingle Jun-Ming Su
Huey-Liang Kuo
Kai-Ling Yang
Chih-Jung Wu
Ya-Fang Ho
Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot study
Digital Health
title Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot study
title_full Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot study
title_fullStr Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot study
title_full_unstemmed Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot study
title_short Interactive decision aid on therapy decision making for patients with chronic kidney disease: A prospective exploratory pilot study
title_sort interactive decision aid on therapy decision making for patients with chronic kidney disease a prospective exploratory pilot study
url https://doi.org/10.1177/20552076251332832
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