Open-lung strategies and mechanical power during protective ventilation for laparoscopic anterior resection: a randomised controlled trial

Open-lung strategies and mechanical power during protective ventilation for laparoscopic anterior resection: a randomised controlled trial

Abstract Higher intraoperative mechanical power (MP) is associated with increased postoperative pulmonary complications (PPCs). We hypothesised that periodic alveolar recruitment manoeuvres (PARM) alone, as an open-lung strategy for intraoperative protective ventilation, would reduce MP, thereby pot...

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Bibliographic Details
Main Authors: Jing Guo, Chu-Ling Liu, Li-Zhen Zhang, Jing Li, Xiao-Ke Gu, Tian-Shuo Wang, Nan-Rong Zhang, Hong Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Alveolar recruitment manoeuvre
Laparoscopic anterior resection
Lung injury biomarker
Mechanical power
Open-lung strategy
Positive end-expiratory pressure
Online Access:https://doi.org/10.1038/s41598-025-13213-x
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