Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer

In order to improve the long–term results of treatment of ductal cancer of the pancreatic head in stage IB–IIA, cryotherapy was performed during gastropancreatoduodenal resections involving the entire pancreatic head tissue in the cold zone. At the same time, freezing was performed twice: 1) before...

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Main Authors: M. D. Khanevich, A. A. Perminova, G. M. Manikhas
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2025-06-01
Series:Вестник хирургии имени И.И. Грекова
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Online Access:https://www.vestnik-grekova.ru/jour/article/view/2454
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author M. D. Khanevich
A. A. Perminova
G. M. Manikhas
author_facet M. D. Khanevich
A. A. Perminova
G. M. Manikhas
author_sort M. D. Khanevich
collection DOAJ
description In order to improve the long–term results of treatment of ductal cancer of the pancreatic head in stage IB–IIA, cryotherapy was performed during gastropancreatoduodenal resections involving the entire pancreatic head tissue in the cold zone. At the same time, freezing was performed twice: 1) before mobilizing the head of the pancreas; 2) after removing the drug on the bed of its removed part. Intraoperative cryotherapy was used in 27 patients with stage IB–IIA ductal cancer. The control group consisted of 31 patients who underwent standard operations without cryoablation. The results of the examination of patients within 7 years of the postoperative period showed the effectiveness of intraoperative cryotherapy on the tumor. Thus, among 10 patients operated on with stage IB of the disease using cryotherapy, tumor recurrence was detected in one patient after five years. While among 12 patients with the same stage, but without cryotherapy, a relapse occurred in 5 patients. The same trend was found in patients operated on during stage IIA of the disease.
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series Вестник хирургии имени И.И. Грекова
spelling doaj-art-aebc1291e5e84ec6969c12e22ad58a742025-08-20T03:23:23ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252025-06-011842717510.24884/0042-4625-2025-184-2-71-751677Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancerM. D. Khanevich0A. A. Perminova1G. M. Manikhas2Saint-Petersburg State Pediatric Medical UniversityCity Clinical Hospital named after S. S. YudinPavlov UniversityIn order to improve the long–term results of treatment of ductal cancer of the pancreatic head in stage IB–IIA, cryotherapy was performed during gastropancreatoduodenal resections involving the entire pancreatic head tissue in the cold zone. At the same time, freezing was performed twice: 1) before mobilizing the head of the pancreas; 2) after removing the drug on the bed of its removed part. Intraoperative cryotherapy was used in 27 patients with stage IB–IIA ductal cancer. The control group consisted of 31 patients who underwent standard operations without cryoablation. The results of the examination of patients within 7 years of the postoperative period showed the effectiveness of intraoperative cryotherapy on the tumor. Thus, among 10 patients operated on with stage IB of the disease using cryotherapy, tumor recurrence was detected in one patient after five years. While among 12 patients with the same stage, but without cryotherapy, a relapse occurred in 5 patients. The same trend was found in patients operated on during stage IIA of the disease.https://www.vestnik-grekova.ru/jour/article/view/2454pancreatic headductal cancercryosurgerygastropancreatoduodenal resection
spellingShingle M. D. Khanevich
A. A. Perminova
G. M. Manikhas
Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer
Вестник хирургии имени И.И. Грекова
pancreatic head
ductal cancer
cryosurgery
gastropancreatoduodenal resection
title Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer
title_full Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer
title_fullStr Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer
title_full_unstemmed Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer
title_short Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer
title_sort cryosurgery for radical gastropancreatoduodenal resections in patients with stage ib iia pancreatic head cancer
topic pancreatic head
ductal cancer
cryosurgery
gastropancreatoduodenal resection
url https://www.vestnik-grekova.ru/jour/article/view/2454
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AT aaperminova cryosurgeryforradicalgastropancreatoduodenalresectionsinpatientswithstageibiiapancreaticheadcancer
AT gmmanikhas cryosurgeryforradicalgastropancreatoduodenalresectionsinpatientswithstageibiiapancreaticheadcancer