Efficacy and safety of immunosuppressive therapy versus cyclosporine combined with avatrombopag in older adults with severe aplastic anemia: a multicenter prospective study
Abstract This trial compared antithymocyte globulin (ATG) + cyclosporine A (CsA) + avatrombopag (AVA) and CsA + AVA in older adults with severe aplastic anemia (SAA). The patients were randomized to receive either ATG + CsA + AVA or CsA + AVA. Of 84 included patients, 42 were treated with ATG + CsA...
Saved in:
| Main Authors: | Leyu Wang, Lei Ye, Xin Zhao, Miao Chen, Fengkui Zhang, Bing Han |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Blood Cancer Journal |
| Online Access: | https://doi.org/10.1038/s41408-025-01328-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Analysis of the efficacy of avatrombopag for the delayed platelet engraftment after allogeneic hematopoietic stem cell transplantation for aplastic anemia
by: Xinhe Zhang, et al.
Published: (2025-08-01) -
Impact of HLA alloimmunization on clinical outcomes of severe aplastic anemia treated with immunosuppressive therapy
by: Jibran Durrani, et al.
Published: (2025-06-01) -
Safety and efficacy of romiplostim in children with acquired aplastic anemia who are naïve to immunosuppressive therapy
by: Mohammadreza Bordbar, et al.
Published: (2025-07-01) -
Efficacy and safety of avatrombopag in combination with immunosuppressive therapy in treatment-naïve and relapsed/refractory severe aplastic anaemia: protocol for the DIAAMOND-Ava-FIRST and DIAAMOND-Ava-NEXT Bayesian Optimal Phase II trials
by: Stephane Heritier, et al.
Published: (2024-01-01) -
High- vs regular-dose recombinant human thrombopoietin plus cyclosporine A in patients with newly diagnosed non-severe aplastic anemia: a retrospective cohort study
by: Yuan Yang, et al.
Published: (2024-12-01)