Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler

Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia,...

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Main Authors: Kristie Searcy, Apoorva Jagadish, Patricia Pichilingue-Reto, Radhakrishna Baliga
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2022/3811170
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author Kristie Searcy
Apoorva Jagadish
Patricia Pichilingue-Reto
Radhakrishna Baliga
author_facet Kristie Searcy
Apoorva Jagadish
Patricia Pichilingue-Reto
Radhakrishna Baliga
author_sort Kristie Searcy
collection DOAJ
description Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia, and end organ damage. This is present in severe cases of COVID-19 and in hemolytic uremic syndrome (HUS) commonly caused by Escherichia coli (E.coli) 0157:H7. We report a novel case of a toddler who presented with classic features suggestive of HUS characterized by bloody diarrhea followed by thrombocytopenia, hemolytic anemia, and acute kidney injury, in whom a polymerase chain reaction (PCR) test for SARS-CoV-2 was positive.
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institution Kabale University
issn 2090-6811
language English
publishDate 2022-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-aeb778d1c3a44d9484a3bcea18cb47b72025-02-03T01:00:43ZengWileyCase Reports in Pediatrics2090-68112022-01-01202210.1155/2022/3811170Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a ToddlerKristie Searcy0Apoorva Jagadish1Patricia Pichilingue-Reto2Radhakrishna Baliga3Department of Internal Medicine and PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsCoronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia, and end organ damage. This is present in severe cases of COVID-19 and in hemolytic uremic syndrome (HUS) commonly caused by Escherichia coli (E.coli) 0157:H7. We report a novel case of a toddler who presented with classic features suggestive of HUS characterized by bloody diarrhea followed by thrombocytopenia, hemolytic anemia, and acute kidney injury, in whom a polymerase chain reaction (PCR) test for SARS-CoV-2 was positive.http://dx.doi.org/10.1155/2022/3811170
spellingShingle Kristie Searcy
Apoorva Jagadish
Patricia Pichilingue-Reto
Radhakrishna Baliga
Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
Case Reports in Pediatrics
title Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_full Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_fullStr Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_full_unstemmed Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_short Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_sort coronavirus disease 2019 covid 19 associated hemolytic uremic syndrome in a toddler
url http://dx.doi.org/10.1155/2022/3811170
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