Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)

The extraction and purification of lactic acid from fermentation processes is crucial for biotechnological product quality and productivity improvement. This mini review focuses on the topic of lactic acid purification processes that incorporate membrane separation technologies. Membrane filtration...

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Main Authors: Nahla. M. Salatein, A.M. Abdelghany, B.M. Elmowafy, Rawan K. Hassan, Ahmed F. Omara, Aziz R. Mansour, Irene S. Fahim
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625002632
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author Nahla. M. Salatein
A.M. Abdelghany
B.M. Elmowafy
Rawan K. Hassan
Ahmed F. Omara
Aziz R. Mansour
Irene S. Fahim
author_facet Nahla. M. Salatein
A.M. Abdelghany
B.M. Elmowafy
Rawan K. Hassan
Ahmed F. Omara
Aziz R. Mansour
Irene S. Fahim
author_sort Nahla. M. Salatein
collection DOAJ
description The extraction and purification of lactic acid from fermentation processes is crucial for biotechnological product quality and productivity improvement. This mini review focuses on the topic of lactic acid purification processes that incorporate membrane separation technologies. Membrane filtration isolates lactic acid from fermentation broth without energy-intensive distillation. Membrane techniques involve microfiltration, ultrafiltration, and nanofiltration. The advantages of membrane technology are examined, including lower operational expenses, reduced thermal degradation of lactic acid, and the potential for continuous operation. This paper summarizes our research on the use of membrane separation systems, particularly microfiltration and nanofiltration, for the separation and concentration of lactic acids from fermentation broths derived from sugarcane molasses. Based on the data collected during our study, we have decided to implement membrane technology as the primary method for separation in our future work to enhance the overall efficiency and sustainability of LA production. This integration is expected to improve both the yield and purity of LA, making the production process more economically viable. Consequently, the adoption of these advanced filtration techniques could lead to a more sustainable approach in the bioprocessing industry.
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publisher Elsevier
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spelling doaj-art-aeb281971f584a4e8f12b706461d79d02025-08-20T02:33:12ZengElsevierResults in Chemistry2211-71562025-05-011510228010.1016/j.rechem.2025.102280Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)Nahla. M. Salatein0A.M. Abdelghany1B.M. Elmowafy2Rawan K. Hassan3Ahmed F. Omara4Aziz R. Mansour5Irene S. Fahim6Smart Engineering Systems Research Center (SESC), Nile University, Cairo, Egypt; Corresponding author.Spectroscopy Department, Physics Research Institute, National Research Centre, 33 Elbehouth St., Dokki, 12311 Giza, EgyptSmart Engineering Systems Research Center (SESC), Nile University, Cairo, EgyptSmart Engineering Systems Research Center (SESC), Nile University, Cairo, EgyptRahki Organization, Cairo, EgyptRahki Organization, Cairo, EgyptSmart Engineering Systems Research Center (SESC), Nile University, Cairo, EgyptThe extraction and purification of lactic acid from fermentation processes is crucial for biotechnological product quality and productivity improvement. This mini review focuses on the topic of lactic acid purification processes that incorporate membrane separation technologies. Membrane filtration isolates lactic acid from fermentation broth without energy-intensive distillation. Membrane techniques involve microfiltration, ultrafiltration, and nanofiltration. The advantages of membrane technology are examined, including lower operational expenses, reduced thermal degradation of lactic acid, and the potential for continuous operation. This paper summarizes our research on the use of membrane separation systems, particularly microfiltration and nanofiltration, for the separation and concentration of lactic acids from fermentation broths derived from sugarcane molasses. Based on the data collected during our study, we have decided to implement membrane technology as the primary method for separation in our future work to enhance the overall efficiency and sustainability of LA production. This integration is expected to improve both the yield and purity of LA, making the production process more economically viable. Consequently, the adoption of these advanced filtration techniques could lead to a more sustainable approach in the bioprocessing industry.http://www.sciencedirect.com/science/article/pii/S2211715625002632Lactic acidSugarcane molassesFermentation brothMembrane separation
spellingShingle Nahla. M. Salatein
A.M. Abdelghany
B.M. Elmowafy
Rawan K. Hassan
Ahmed F. Omara
Aziz R. Mansour
Irene S. Fahim
Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)
Results in Chemistry
Lactic acid
Sugarcane molasses
Fermentation broth
Membrane separation
title Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)
title_full Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)
title_fullStr Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)
title_full_unstemmed Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)
title_short Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)
title_sort lactic acid separation technologies enhancing efficiency and purity using membrane separation technology mini review
topic Lactic acid
Sugarcane molasses
Fermentation broth
Membrane separation
url http://www.sciencedirect.com/science/article/pii/S2211715625002632
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