Evaluation of Haematological and Immunological Status in Type 2 Diabetics
Type 2 diabetes is a heterogeneous disorder involving impairment of both insulin secretion and insulin action. The immunological and haematological statuses during normal and diseased conditions have been studied. The study groups consisted of 220 patients (110 males, 110 females) and 220 age and s...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
|
| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/576150 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564139266932736 |
|---|---|
| author | A. Sohna Chandra Packiavathy M. Ramalingam |
| author_facet | A. Sohna Chandra Packiavathy M. Ramalingam |
| author_sort | A. Sohna Chandra Packiavathy |
| collection | DOAJ |
| description | Type 2 diabetes is a heterogeneous disorder involving impairment of both insulin secretion and insulin action. The immunological and haematological statuses during normal and diseased conditions have been studied. The study groups consisted of 220 patients (110 males, 110 females) and 220 age and sex matched control subjects (110 males, 110 females). The values of IgG, IgM, IgE and IgA were found to be significantly increased. Leucocyte count and erythrocyte sedimentation rate were also found to be increased in the type 2 diabetics as compared to controls. The study suggests that variation in the levels of immunoglobulins and cell count may be involved in the pathogenesis of type 2 diabetes mellitus. |
| format | Article |
| id | doaj-art-aeafe04e56a94c65979c51539db52472 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-aeafe04e56a94c65979c51539db524722025-02-03T01:11:39ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-01731029103210.1155/2010/576150Evaluation of Haematological and Immunological Status in Type 2 DiabeticsA. Sohna Chandra Packiavathy0M. Ramalingam1Department of Biochemistry, PRIST University, Thanjavur-614904, IndiaCenter for Research and Development, PRIST University, Vallam, Thanjavur-613103, IndiaType 2 diabetes is a heterogeneous disorder involving impairment of both insulin secretion and insulin action. The immunological and haematological statuses during normal and diseased conditions have been studied. The study groups consisted of 220 patients (110 males, 110 females) and 220 age and sex matched control subjects (110 males, 110 females). The values of IgG, IgM, IgE and IgA were found to be significantly increased. Leucocyte count and erythrocyte sedimentation rate were also found to be increased in the type 2 diabetics as compared to controls. The study suggests that variation in the levels of immunoglobulins and cell count may be involved in the pathogenesis of type 2 diabetes mellitus.http://dx.doi.org/10.1155/2010/576150 |
| spellingShingle | A. Sohna Chandra Packiavathy M. Ramalingam Evaluation of Haematological and Immunological Status in Type 2 Diabetics E-Journal of Chemistry |
| title | Evaluation of Haematological and Immunological Status in Type 2 Diabetics |
| title_full | Evaluation of Haematological and Immunological Status in Type 2 Diabetics |
| title_fullStr | Evaluation of Haematological and Immunological Status in Type 2 Diabetics |
| title_full_unstemmed | Evaluation of Haematological and Immunological Status in Type 2 Diabetics |
| title_short | Evaluation of Haematological and Immunological Status in Type 2 Diabetics |
| title_sort | evaluation of haematological and immunological status in type 2 diabetics |
| url | http://dx.doi.org/10.1155/2010/576150 |
| work_keys_str_mv | AT asohnachandrapackiavathy evaluationofhaematologicalandimmunologicalstatusintype2diabetics AT mramalingam evaluationofhaematologicalandimmunologicalstatusintype2diabetics |