The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients
Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections – one Candida parapsilosis complex infection and one Aspergillus fumigatus...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Medical Mycology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753925000119 |
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| author | Jay Krishnan Manuela Carugati Rachel A. Miller Cameron R. Wolfe John R. Perfect Julia A. Messina |
| author_facet | Jay Krishnan Manuela Carugati Rachel A. Miller Cameron R. Wolfe John R. Perfect Julia A. Messina |
| author_sort | Jay Krishnan |
| collection | DOAJ |
| description | Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections – one Candida parapsilosis complex infection and one Aspergillus fumigatus infection – that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy. |
| format | Article |
| id | doaj-art-aead526fce2a424d90d95cb9c64a2ab0 |
| institution | OA Journals |
| issn | 2211-7539 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj-art-aead526fce2a424d90d95cb9c64a2ab02025-08-20T02:06:20ZengElsevierMedical Mycology Case Reports2211-75392025-06-014810070210.1016/j.mmcr.2025.100702The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipientsJay Krishnan0Manuela Carugati1Rachel A. Miller2Cameron R. Wolfe3John R. Perfect4Julia A. Messina5Duke University, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USADuke University, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USADuke University, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USADuke University, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USADuke University, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USACorresponding author. Box DUMC 102359, Durham, NC, 27710, USA.; Duke University, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USADonor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections – one Candida parapsilosis complex infection and one Aspergillus fumigatus infection – that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy.http://www.sciencedirect.com/science/article/pii/S2211753925000119Donor-derived fungal infectionOrthotopic heart transplantationCandida parapsilosis complexAspergillus fumigatusFungal endocarditis |
| spellingShingle | Jay Krishnan Manuela Carugati Rachel A. Miller Cameron R. Wolfe John R. Perfect Julia A. Messina The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients Medical Mycology Case Reports Donor-derived fungal infection Orthotopic heart transplantation Candida parapsilosis complex Aspergillus fumigatus Fungal endocarditis |
| title | The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients |
| title_full | The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients |
| title_fullStr | The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients |
| title_full_unstemmed | The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients |
| title_short | The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients |
| title_sort | tell tale hearts donor derived invasive fungal infections among orthotopic heart transplant recipients |
| topic | Donor-derived fungal infection Orthotopic heart transplantation Candida parapsilosis complex Aspergillus fumigatus Fungal endocarditis |
| url | http://www.sciencedirect.com/science/article/pii/S2211753925000119 |
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