CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapy

CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapy

Approximately 20% of locally advanced rectal cancer (LARC) patients treated preoperatively with chemoradiotherapy (CRT) achieve pathologically confirmed complete regression. However, there are no clinically implemented biomarkers measurable in biopsies that are predictive of tumor regression. Here,...

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Bibliographic Details
Main Authors: Benita C. Y. Tse, Sarah Bergamin, Pascal Steffen, George Hruby, Nick Pavlakis, Stephen J. Clarke, Justin Evans, Alexander Engel, Andrew Kneebone, Mark P. Molloy
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Dendritic cell
immune cell
immunophenotype
neoadjuvant chemoradiotherapy
rectal cancer
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2238506
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