Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma

Malignant melanoma of the conjunctiva is a rare tumor of the ocular surface with potential fatal consequences and a high likelihood of recurrence. Although routes for extending the tumor, including local, hematogenous, and lymphatogenous, are pretty straightforward, the indirect extension through fr...

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Main Authors: Amirreza Veisi, Zahra Dastborhan, Mohsen Dastmardi, Mozhgan Rezaie Kanavi, Saeid Rezaei
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2024/1034939
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author Amirreza Veisi
Zahra Dastborhan
Mohsen Dastmardi
Mozhgan Rezaie Kanavi
Saeid Rezaei
author_facet Amirreza Veisi
Zahra Dastborhan
Mohsen Dastmardi
Mozhgan Rezaie Kanavi
Saeid Rezaei
author_sort Amirreza Veisi
collection DOAJ
description Malignant melanoma of the conjunctiva is a rare tumor of the ocular surface with potential fatal consequences and a high likelihood of recurrence. Although routes for extending the tumor, including local, hematogenous, and lymphatogenous, are pretty straightforward, the indirect extension through free-floating tumoral cells to the nasolacrimal duct is not described thoroughly. We report a case of malignant melanoma of the conjunctiva which presented with local recurrence in the intranasal cavity and lacrimal sac two years after the primary surgery (without involvement of the ocular surface and punctum on the second occasion). However, there was no evidence of distant metastasis on either occasion. This case demonstrates the possible noncontiguous spreading route of melanoma tumoral cells and highlights the need for attention to the surgical technique, and careful follow-up to detect further disease activity.
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id doaj-art-ae854edebf054bc0be13955986f29ae5
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issn 2090-6730
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publishDate 2024-01-01
publisher Wiley
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-ae854edebf054bc0be13955986f29ae52025-08-20T02:23:08ZengWileyCase Reports in Ophthalmological Medicine2090-67302024-01-01202410.1155/2024/1034939Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival MelanomaAmirreza Veisi0Zahra Dastborhan1Mohsen Dastmardi2Mozhgan Rezaie Kanavi3Saeid Rezaei4Ophthalmic Research CenterOphthalmic Research CenterShahid Beheshti University of Medical SciencesOcular Tissue Engineering Research CenterEye and Skull Base Research CentersMalignant melanoma of the conjunctiva is a rare tumor of the ocular surface with potential fatal consequences and a high likelihood of recurrence. Although routes for extending the tumor, including local, hematogenous, and lymphatogenous, are pretty straightforward, the indirect extension through free-floating tumoral cells to the nasolacrimal duct is not described thoroughly. We report a case of malignant melanoma of the conjunctiva which presented with local recurrence in the intranasal cavity and lacrimal sac two years after the primary surgery (without involvement of the ocular surface and punctum on the second occasion). However, there was no evidence of distant metastasis on either occasion. This case demonstrates the possible noncontiguous spreading route of melanoma tumoral cells and highlights the need for attention to the surgical technique, and careful follow-up to detect further disease activity.http://dx.doi.org/10.1155/2024/1034939
spellingShingle Amirreza Veisi
Zahra Dastborhan
Mohsen Dastmardi
Mozhgan Rezaie Kanavi
Saeid Rezaei
Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma
Case Reports in Ophthalmological Medicine
title Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma
title_full Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma
title_fullStr Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma
title_full_unstemmed Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma
title_short Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma
title_sort lacrimal drainage system and nasal cavity melanoma after complete treatment of conjunctival melanoma
url http://dx.doi.org/10.1155/2024/1034939
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