High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update
Carbapenem-resistant Pseudomonas aeruginosa is defined by the World Health Organization as a “high priority” in developing new antimicrobials. Indeed, the emergence and spread of multidrug-resistant (MDR) or extensively drug-resistant (XDR) bacteria increase the morbidity and mortality risk of infec...
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| Language: | English |
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Elsevier
2025-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024175718 |
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| author | Verónica Roxana Flores-Vega Santiago Partida-Sanchez Miguel A. Ares Vianney Ortiz-Navarrete Roberto Rosales-Reyes |
| author_facet | Verónica Roxana Flores-Vega Santiago Partida-Sanchez Miguel A. Ares Vianney Ortiz-Navarrete Roberto Rosales-Reyes |
| author_sort | Verónica Roxana Flores-Vega |
| collection | DOAJ |
| description | Carbapenem-resistant Pseudomonas aeruginosa is defined by the World Health Organization as a “high priority” in developing new antimicrobials. Indeed, the emergence and spread of multidrug-resistant (MDR) or extensively drug-resistant (XDR) bacteria increase the morbidity and mortality risk of infected patients. Genomic variants of P. aeruginosa that display phenotypes of MDR/XDR have been defined as high-risk global clones. In this mini-review, we describe some international high-risk clones that carry β-lactamase genes that can produce chronic colonization and increase infected patients' morbidity and mortality rates. |
| format | Article |
| id | doaj-art-ae805b5331d84912969c6bf68315afdf |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-ae805b5331d84912969c6bf68315afdf2025-01-17T04:51:35ZengElsevierHeliyon2405-84402025-01-01111e41540High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 updateVerónica Roxana Flores-Vega0Santiago Partida-Sanchez1Miguel A. Ares2Vianney Ortiz-Navarrete3Roberto Rosales-Reyes4Unidad de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico; Departamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del IPN, Mexico City, MexicoCenter for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USAUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, MexicoDepartamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del IPN, Mexico City, MexicoUnidad de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico; Corresponding author.Carbapenem-resistant Pseudomonas aeruginosa is defined by the World Health Organization as a “high priority” in developing new antimicrobials. Indeed, the emergence and spread of multidrug-resistant (MDR) or extensively drug-resistant (XDR) bacteria increase the morbidity and mortality risk of infected patients. Genomic variants of P. aeruginosa that display phenotypes of MDR/XDR have been defined as high-risk global clones. In this mini-review, we describe some international high-risk clones that carry β-lactamase genes that can produce chronic colonization and increase infected patients' morbidity and mortality rates.http://www.sciencedirect.com/science/article/pii/S2405844024175718Pseudomonas aeruginosaSequence typeHigh-riskMultidrug resistanceβ-Lactamase genes |
| spellingShingle | Verónica Roxana Flores-Vega Santiago Partida-Sanchez Miguel A. Ares Vianney Ortiz-Navarrete Roberto Rosales-Reyes High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update Heliyon Pseudomonas aeruginosa Sequence type High-risk Multidrug resistance β-Lactamase genes |
| title | High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update |
| title_full | High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update |
| title_fullStr | High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update |
| title_full_unstemmed | High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update |
| title_short | High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update |
| title_sort | high risk pseudomonas aeruginosa clones harboring β lactamases 2024 update |
| topic | Pseudomonas aeruginosa Sequence type High-risk Multidrug resistance β-Lactamase genes |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024175718 |
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