Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future
OBJECTIVES: The history behind the current understanding of the varicella-zoster virus and its relationship to the pain conditions caused by shingles and postherpetic neuralgia are reviewed. The framework for the current conceptualization is Hope-Simpson’s latency hypothesis. Data from recent work i...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2009/380384 |
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| _version_ | 1832549325642661888 |
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| author | Gary J Bennett C Peter N Watson |
| author_facet | Gary J Bennett C Peter N Watson |
| author_sort | Gary J Bennett |
| collection | DOAJ |
| description | OBJECTIVES: The history behind the current understanding of the varicella-zoster virus and its relationship to the pain conditions caused by shingles and postherpetic neuralgia are reviewed. The framework for the current conceptualization is Hope-Simpson’s latency hypothesis. Data from recent work in virology, neuroanatomy and epidemiology are reviewed, as is work using varicella-zoster virus-infected animals. The recent data largely confirm Hope-Simpson’s hypothesis and extend it significantly. |
| format | Article |
| id | doaj-art-ae7cb059988542b58bb24577dfed9e85 |
| institution | Kabale University |
| issn | 1203-6765 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-ae7cb059988542b58bb24577dfed9e852025-02-03T06:11:40ZengWileyPain Research and Management1203-67652009-01-0114427528210.1155/2009/380384Herpes Zoster and Postherpetic Neuralgia: Past, Present and FutureGary J Bennett0C Peter N Watson1Department of Anesthesia, Faculty of Dentistry, and The Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, CanadaDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaOBJECTIVES: The history behind the current understanding of the varicella-zoster virus and its relationship to the pain conditions caused by shingles and postherpetic neuralgia are reviewed. The framework for the current conceptualization is Hope-Simpson’s latency hypothesis. Data from recent work in virology, neuroanatomy and epidemiology are reviewed, as is work using varicella-zoster virus-infected animals. The recent data largely confirm Hope-Simpson’s hypothesis and extend it significantly.http://dx.doi.org/10.1155/2009/380384 |
| spellingShingle | Gary J Bennett C Peter N Watson Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future Pain Research and Management |
| title | Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future |
| title_full | Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future |
| title_fullStr | Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future |
| title_full_unstemmed | Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future |
| title_short | Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future |
| title_sort | herpes zoster and postherpetic neuralgia past present and future |
| url | http://dx.doi.org/10.1155/2009/380384 |
| work_keys_str_mv | AT garyjbennett herpeszosterandpostherpeticneuralgiapastpresentandfuture AT cpeternwatson herpeszosterandpostherpeticneuralgiapastpresentandfuture |