Systematic suppression of Leishmania (Leishmania) amazonensis-mediated delayed-type hypersensitivity response in American cutaneous leishmaniasis

Systematic suppression of Leishmania (Leishmania) amazonensis-mediated delayed-type hypersensitivity response in American cutaneous leishmaniasis

Abstract Background American cutaneous leishmaniasis (ACL) is a protozoan parasitic disease caused by different Leishmania spp. from L. (Leishmania) and L. (Viannia) subgenera. In Brazil, seven Leishmania spp. act as ACL agents. Infection with L. (L.) amazonensis presents a wide clinical–immunopatho...

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Bibliographic Details
Main Authors: Marliane B. Campos, Luciana V. R. Lima, Thiago Vasconcelos dos Santos, Patrícia K. Ramos, Claudia M. C. Gomes, Márcia D. Laurenti, Carlos E. P. Corbett, Jeffrey J. Shaw, Fernando T. Silveira
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Parasites & Vectors
Subjects:
Leishmania (L.) amazonensis
Systematic suppression
T-cell immune response
Delayed-type hypersensitivity
American cutaneous leishmaniasis
Online Access:https://doi.org/10.1186/s13071-025-06941-6
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