AMELIORATIVE ROLE OF SCHIFF-BASE DERIVED FROM PHENYL ETHYL AMINE AGAINST SODIUM NITRATE TOXICITY IN LABORATORY MALE RATS
This study was designed to Evaluate the biological activity of Schiff base derived fromphenyl ethyl amine produced novel compound used in this experiment. Thirty adult male ratsage (10-14) weeks (150-200) gm weights were included and separate randomly into 5 groups (6rats / group) and treated for 21...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
College of Veterinary Medicine, University of Basrah, Iraq
2020-11-01
|
| Series: | Basrah Journal of Veterinary Research |
| Subjects: | |
| Online Access: | https://bjvr.uobasrah.edu.iq/article_174111_f444f7b78d9c65c8533f0fa24a388ba6.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | This study was designed to Evaluate the biological activity of Schiff base derived fromphenyl ethyl amine produced novel compound used in this experiment. Thirty adult male ratsage (10-14) weeks (150-200) gm weights were included and separate randomly into 5 groups (6rats / group) and treated for 21days intraperitoneally (I.P) as follows:- Group 1 (control):0.5ml/day of DMSO daily ,Group 2: 18mg/kg of NaNO2, daily ,Group 3 94 mg/kg of phenylethyl amine daily ,Group 4 18 mg/kg of NaNO2, then after one hour 0.5ml/day from 66.8mg/kgof synthesis compound daily , Group 5: 0.5ml/day from 66.8mg/kg of synthesized compound.According to finding Results there was significant ameliorative effects of Schiff base againstsodium nitrate toxicity in several physiological parameters as (R.B.C. count , Hb. concentration ,PCV. ,W.B.C. count MID%, TSH,T3 andT4 levels ) which the result showed there weresignificant decreased in this parameters in group 5 where administrate sodium nitrate and afterone hour novel compound in compared with group 2 sodium nitrate alone . |
|---|---|
| ISSN: | 1813-8497 2410-8456 |