Recanalization and reperfusion in clinically-relevant porcine model of stroke

Recanalization and reperfusion in clinically-relevant porcine model of stroke

IntroductionStroke is a leading cause of death and long-term disability. Pigs have been considered an ideal large animal model in biomedicine; however, the complex vascular anatomy has posed challenges for stroke research. Nonetheless, we have previously overcome these limitations and demonstrated t...

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Main Authors: Błażej Nowak, Piotr Holak, Izabela Małysz-Cymborska, Alexandra Chovsepian, Yanina Dening, Jarosław Olszewski, Aleksandra Piecuch, Maria Jasieniak, Jakub Jasieniak, Arkadiusz Szterk, Maria Sady, Karolina Ferenc, Daniel Berchtold, Artur Jabłoński, Romuald Zabielski, Zdzisław Gajewski, Tim Magnus, Mirosław Janowski, Piotr Walczak, Andreas Meisel, Francisco Pan-Montojo, Dominika Gołubczyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Neuroscience
Subjects:
acute stroke therapy
ischaemic stroke
MRI
radiology
reperfusion
rtPA
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1572925/full
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