Extracellular Vesicles from Adipose-Derived Mesenchymal Stem/Stromal Cells Accelerate Migration and Activate AKT Pathway in Human Keratinocytes and Fibroblasts Independently of miR-205 Activity

Extracellular Vesicles from Adipose-Derived Mesenchymal Stem/Stromal Cells Accelerate Migration and Activate AKT Pathway in Human Keratinocytes and Fibroblasts Independently of miR-205 Activity

Mesenchymal stem/stromal cells (MSCs) are promising tools in cell therapy. They secrete extracellular vesicles (EVs) that carry different classes of molecules that can promote skin repair, but the mechanisms are poorly understood. Skin wound healing is a complex process that requires the activity of...

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Main Authors: Andrea da Fonseca Ferreira, Pricila da Silva Cunha, Virgínia Mendes Carregal, Priscila de Cássia da Silva, Marcelo Coutinho de Miranda, Marianna Kunrath-Lima, Mariane Izabella Abreu de Melo, Camila Cristina Fraga Faraco, Joana Lobato Barbosa, Frédéric Frezard, Vivian Resende, Michele Angela Rodrigues, Alfredo Miranda de Goes, Dawidson Assis Gomes
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/9841035
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