Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in Pregnancy

Autoimmune hemolytic anemia (AIHA) is a rare disorder during pregnancy. The management of AIHA in pregnancy is not well established and remains challenging. A 30- year-old woman presented with severe AIHA at 10 weeks of gestation. Bilateral adnexal cysts were identified on pelvic ultrasound. She rec...

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Main Authors: Mohammad Alhomoud, Rochelle Joly, Maria Teresa DeSancho
Format: Article
Language:English
Published: American College of Physicians 2023-08-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.1095
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author Mohammad Alhomoud
Rochelle Joly
Maria Teresa DeSancho
author_facet Mohammad Alhomoud
Rochelle Joly
Maria Teresa DeSancho
author_sort Mohammad Alhomoud
collection DOAJ
description Autoimmune hemolytic anemia (AIHA) is a rare disorder during pregnancy. The management of AIHA in pregnancy is not well established and remains challenging. A 30- year-old woman presented with severe AIHA at 10 weeks of gestation. Bilateral adnexal cysts were identified on pelvic ultrasound. She received prednisone and intravenous immunoglobulin without any improvement. She developed preeclampsia at 26 weeks of gestation and delivered at 29 weeks. She received rituximab postpartum and showed no signs of improvement. Five months later, she developed abdominal pain. Computed tomographyof the abdomen and pelvis revealed cholelithiasis, splenomegaly, and bilateral adnexal cystic masses. The removal of bilateral ovarian dermoid cysts successfully resolved the AIHA. It is important to recognize that dermoid cysts can potentially lead to AIHA during pregnancy. To reduce health risks for the mother and fetus, it may be necessary to promptly remove these cysts through surgery instead of resorting to unnecessary immunosuppressive treatments.
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spelling doaj-art-ae652a92922e4c58a2a9f2f710f04ab32025-08-20T02:27:24ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642023-08-012810.7326/aimcc.2022.1095Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in PregnancyMohammad Alhomoud0Rochelle Joly1Maria Teresa DeSancho21Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, New York2Department of Obstetrics and Gynecology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, New York1Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, New YorkAutoimmune hemolytic anemia (AIHA) is a rare disorder during pregnancy. The management of AIHA in pregnancy is not well established and remains challenging. A 30- year-old woman presented with severe AIHA at 10 weeks of gestation. Bilateral adnexal cysts were identified on pelvic ultrasound. She received prednisone and intravenous immunoglobulin without any improvement. She developed preeclampsia at 26 weeks of gestation and delivered at 29 weeks. She received rituximab postpartum and showed no signs of improvement. Five months later, she developed abdominal pain. Computed tomographyof the abdomen and pelvis revealed cholelithiasis, splenomegaly, and bilateral adnexal cystic masses. The removal of bilateral ovarian dermoid cysts successfully resolved the AIHA. It is important to recognize that dermoid cysts can potentially lead to AIHA during pregnancy. To reduce health risks for the mother and fetus, it may be necessary to promptly remove these cysts through surgery instead of resorting to unnecessary immunosuppressive treatments.https://www.acpjournals.org/doi/10.7326/aimcc.2022.1095
spellingShingle Mohammad Alhomoud
Rochelle Joly
Maria Teresa DeSancho
Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in Pregnancy
Annals of Internal Medicine: Clinical Cases
title Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in Pregnancy
title_full Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in Pregnancy
title_fullStr Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in Pregnancy
title_full_unstemmed Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in Pregnancy
title_short Dermoid Cysts and Refractory Warm Autoimmune Hemolytic Anemia in Pregnancy
title_sort dermoid cysts and refractory warm autoimmune hemolytic anemia in pregnancy
url https://www.acpjournals.org/doi/10.7326/aimcc.2022.1095
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AT rochellejoly dermoidcystsandrefractorywarmautoimmunehemolyticanemiainpregnancy
AT mariateresadesancho dermoidcystsandrefractorywarmautoimmunehemolyticanemiainpregnancy