Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in Kenya

Background: Salmonellosis is considered one of the most widespread food-borne zoonoses in industrialized as well as developing countries. The presence of Salmonella in food animals at slaughter and the consequent cross-contamination of edible carcass tissues present a significant food safety hazard...

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Main Authors: Gideon M. Kikuvi, Jackson N. Ombui, Eric S. Mitema
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2010-03-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/446
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author Gideon M. Kikuvi
Jackson N. Ombui
Eric S. Mitema
author_facet Gideon M. Kikuvi
Jackson N. Ombui
Eric S. Mitema
author_sort Gideon M. Kikuvi
collection DOAJ
description Background: Salmonellosis is considered one of the most widespread food-borne zoonoses in industrialized as well as developing countries. The presence of Salmonella in food animals at slaughter and the consequent cross-contamination of edible carcass tissues present a significant food safety hazard. Methodology: Samples were collected from randomly selected pigs at the Ndumbuini abattoir in Nairobi. Isolates were confirmed to be Salmonella by biochemical tests and characterised by serotyping, phage typing and plasmid analysis. Minimum inhibitory concentrations (MICs) of eight antimicrobials were determined and the resistant isolates were screened for resistance genes by PCR. Results: Sixteen (13.8%) of 116 samples were positive for Salmonella. Three Salmonella enterica subsp. enterica serovars, namely Saintpaul, Braenderup, and Heidelberg were identified, S. Saintpaul being predominant. Antimicrobial resistance was found in 35.7% of the isolates. The S. Heidelberg isolates were susceptible to all the antimicrobials tested. Multidrug resistance was found in 7.1% of the Salmonella isolates. Plasmids were only detected in S. Heidelberg. Ampicillin resistance was based on expression of a blaTEM gene, while chloramphenicol, streptomycin, and tetracycline resistances were encoded by the genes catA1, strA, and tet(A), respectively. Conclusions: Pigs may serve as reservoirs of antimicrobial resistant Salmonella and slaughterhouse cross-contamination of pork may be a food safety risk.
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spelling doaj-art-ae63bb2cbefd420da644d13629257a262025-08-20T02:27:15ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802010-03-0140410.3855/jidc.446Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in KenyaGideon M. Kikuvi0Jackson N. Ombui1Eric S. Mitema2Jomo Kenyatta University of Agriculture and Technology, NairobiUniversity of NairobiUniversity of Nairobi Background: Salmonellosis is considered one of the most widespread food-borne zoonoses in industrialized as well as developing countries. The presence of Salmonella in food animals at slaughter and the consequent cross-contamination of edible carcass tissues present a significant food safety hazard. Methodology: Samples were collected from randomly selected pigs at the Ndumbuini abattoir in Nairobi. Isolates were confirmed to be Salmonella by biochemical tests and characterised by serotyping, phage typing and plasmid analysis. Minimum inhibitory concentrations (MICs) of eight antimicrobials were determined and the resistant isolates were screened for resistance genes by PCR. Results: Sixteen (13.8%) of 116 samples were positive for Salmonella. Three Salmonella enterica subsp. enterica serovars, namely Saintpaul, Braenderup, and Heidelberg were identified, S. Saintpaul being predominant. Antimicrobial resistance was found in 35.7% of the isolates. The S. Heidelberg isolates were susceptible to all the antimicrobials tested. Multidrug resistance was found in 7.1% of the Salmonella isolates. Plasmids were only detected in S. Heidelberg. Ampicillin resistance was based on expression of a blaTEM gene, while chloramphenicol, streptomycin, and tetracycline resistances were encoded by the genes catA1, strA, and tet(A), respectively. Conclusions: Pigs may serve as reservoirs of antimicrobial resistant Salmonella and slaughterhouse cross-contamination of pork may be a food safety risk. https://jidc.org/index.php/journal/article/view/446SerotypesAntimicrobial ResistanceSalmonellaPigsKenya
spellingShingle Gideon M. Kikuvi
Jackson N. Ombui
Eric S. Mitema
Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in Kenya
Journal of Infection in Developing Countries
Serotypes
Antimicrobial Resistance
Salmonella
Pigs
Kenya
title Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in Kenya
title_full Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in Kenya
title_fullStr Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in Kenya
title_full_unstemmed Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in Kenya
title_short Serotypes and antimicrobial resistance profiles of Salmonella isolates from pigs at slaughter in Kenya
title_sort serotypes and antimicrobial resistance profiles of salmonella isolates from pigs at slaughter in kenya
topic Serotypes
Antimicrobial Resistance
Salmonella
Pigs
Kenya
url https://jidc.org/index.php/journal/article/view/446
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