Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study

Conclusion: Survival at 1 and 5 years was lower in patients with PH. However, no significant differences in survival were observed based on sex, mPAP, age, or BMI. Statistically significant improvements in FVC, FEV1, 6MWT, and SGRQ total scores were observed both before and after LT, continuing thro...

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Main Authors: Fabio Varón-Vega, Luis J. Telléz, Eduardo Tuta-Quintero, Adriana Rincón, Diana Casas, Camilo Rodriguez, David Mendoza, Luis Fernando Giraldo-Cadavid
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/carj/1861990
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author Fabio Varón-Vega
Luis J. Telléz
Eduardo Tuta-Quintero
Adriana Rincón
Diana Casas
Camilo Rodriguez
David Mendoza
Luis Fernando Giraldo-Cadavid
author_facet Fabio Varón-Vega
Luis J. Telléz
Eduardo Tuta-Quintero
Adriana Rincón
Diana Casas
Camilo Rodriguez
David Mendoza
Luis Fernando Giraldo-Cadavid
author_sort Fabio Varón-Vega
collection DOAJ
description Conclusion: Survival at 1 and 5 years was lower in patients with PH. However, no significant differences in survival were observed based on sex, mPAP, age, or BMI. Statistically significant improvements in FVC, FEV1, 6MWT, and SGRQ total scores were observed both before and after LT, continuing through 1 year of follow-up. The 6MWT and SGRQ showed MCID both prior to surgery and during follow-up at 6 and 12 months, in both PH and non-PH patients.
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spelling doaj-art-ae5aa0ed9edd407cb6ed0892e34a299b2025-08-20T02:02:12ZengWileyCanadian Respiratory Journal1916-72452025-01-01202510.1155/carj/1861990Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort StudyFabio Varón-Vega0Luis J. Telléz1Eduardo Tuta-Quintero2Adriana Rincón3Diana Casas4Camilo Rodriguez5David Mendoza6Luis Fernando Giraldo-Cadavid7Critical Care and Lung Transplantation ServiceThoracic Surgery ServiceCritical Care ServiceCritical Care and Lung Transplantation ServiceSchool of MedicineCritical Care ServiceCritical Care ServiceSchool of MedicineConclusion: Survival at 1 and 5 years was lower in patients with PH. However, no significant differences in survival were observed based on sex, mPAP, age, or BMI. Statistically significant improvements in FVC, FEV1, 6MWT, and SGRQ total scores were observed both before and after LT, continuing through 1 year of follow-up. The 6MWT and SGRQ showed MCID both prior to surgery and during follow-up at 6 and 12 months, in both PH and non-PH patients.http://dx.doi.org/10.1155/carj/1861990
spellingShingle Fabio Varón-Vega
Luis J. Telléz
Eduardo Tuta-Quintero
Adriana Rincón
Diana Casas
Camilo Rodriguez
David Mendoza
Luis Fernando Giraldo-Cadavid
Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study
Canadian Respiratory Journal
title Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study
title_full Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study
title_fullStr Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study
title_full_unstemmed Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study
title_short Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study
title_sort impact of pulmonary hypertension on posttransplant survival of patients with pulmonary fibrosis at high altitude a prospective cohort study
url http://dx.doi.org/10.1155/carj/1861990
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