HDAC3 inhibitors induce drug resistance by promoting IL-17 A production by T cells

HDAC3 inhibitors induce drug resistance by promoting IL-17 A production by T cells

Abstract HDAC3 has been demonstrated to play a crucial role in the progression of various tumors and the differentiation and development of T cells. However, its impact on peripheral T cells in the development of murine lung cancer remains unclear. In this experiment, a subcutaneous lung tumor model...

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Bibliographic Details
Main Authors: Hao Chen, Anqi Qin, Fan Xu, Shuai Guo, Ge Zhang, Aihong Zhang, WenTing Li, Feng Tian, Quanhui Zheng
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-83447-8
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