A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality control
A practical colorimetric analysis for alcohol determination was devised using a composite of food colorants, specifically a green solution of brilliant blue FCF and tartrazine at a ratio of 1:5 v/v. This colorimetric method was characterized by its simplicity, user-friendliness, environmental compat...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Green Chemistry Letters and Reviews |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/17518253.2023.2298982 |
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| author | Warongrit Sukma Cheerapa Boonyakong Thitiphan Chaiphet Supakarn Chamni |
| author_facet | Warongrit Sukma Cheerapa Boonyakong Thitiphan Chaiphet Supakarn Chamni |
| author_sort | Warongrit Sukma |
| collection | DOAJ |
| description | A practical colorimetric analysis for alcohol determination was devised using a composite of food colorants, specifically a green solution of brilliant blue FCF and tartrazine at a ratio of 1:5 v/v. This colorimetric method was characterized by its simplicity, user-friendliness, environmental compatibility, cost-effectiveness, and suitability for self-measurement through visual examination. The colorimetric procedure entails admixture 1 mL of the alcohol sample with 50 µL of the green test solution and 250 µL of a 30% NaOH solution at ambient temperature. The ensuing color changes were visually assessed within 5 min. Through color sensing, methanol, ethanol, and isopropanol were identified by the manifestation of lemon yellow, orange, and biphasic solutions, respectively. Ethanol was semi-quantified based on color sensing from green to orange, with corresponding concentration ranges. The limit of detection for both methanol and ethanol was determined to be 30% v/v. The developed method demonstrated an accuracy of 93%, with the error range of 1 − 10% v/v and standard deviation of 3.9% v/v, as confirmed by the analysis of 100 commercially available alcohol-based hand sanitizers. This methodology has the potential for further expansion to encompass a wide range of rapid colorimetric analyses of products containing alcohol, including food items, alcohol raw materials, and cosmetics. |
| format | Article |
| id | doaj-art-ae54d259245f4076b1c7c9f08acda69f |
| institution | OA Journals |
| issn | 1751-8253 1751-7192 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Green Chemistry Letters and Reviews |
| spelling | doaj-art-ae54d259245f4076b1c7c9f08acda69f2025-08-20T02:19:38ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922024-12-0117110.1080/17518253.2023.2298982A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality controlWarongrit Sukma0Cheerapa Boonyakong1Thitiphan Chaiphet2Supakarn Chamni3Pharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, ThailandDepartment of Chemical Metrology and Biometry, National Institute of Metrology, Pathum Thani, ThailandDepartment of Chemical Metrology and Biometry, National Institute of Metrology, Pathum Thani, ThailandPharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, ThailandA practical colorimetric analysis for alcohol determination was devised using a composite of food colorants, specifically a green solution of brilliant blue FCF and tartrazine at a ratio of 1:5 v/v. This colorimetric method was characterized by its simplicity, user-friendliness, environmental compatibility, cost-effectiveness, and suitability for self-measurement through visual examination. The colorimetric procedure entails admixture 1 mL of the alcohol sample with 50 µL of the green test solution and 250 µL of a 30% NaOH solution at ambient temperature. The ensuing color changes were visually assessed within 5 min. Through color sensing, methanol, ethanol, and isopropanol were identified by the manifestation of lemon yellow, orange, and biphasic solutions, respectively. Ethanol was semi-quantified based on color sensing from green to orange, with corresponding concentration ranges. The limit of detection for both methanol and ethanol was determined to be 30% v/v. The developed method demonstrated an accuracy of 93%, with the error range of 1 − 10% v/v and standard deviation of 3.9% v/v, as confirmed by the analysis of 100 commercially available alcohol-based hand sanitizers. This methodology has the potential for further expansion to encompass a wide range of rapid colorimetric analyses of products containing alcohol, including food items, alcohol raw materials, and cosmetics.https://www.tandfonline.com/doi/10.1080/17518253.2023.2298982AlcoholFood coloringColorimetric analysisQuick testAlcohol-based hand sanitizer |
| spellingShingle | Warongrit Sukma Cheerapa Boonyakong Thitiphan Chaiphet Supakarn Chamni A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality control Green Chemistry Letters and Reviews Alcohol Food coloring Colorimetric analysis Quick test Alcohol-based hand sanitizer |
| title | A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality control |
| title_full | A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality control |
| title_fullStr | A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality control |
| title_full_unstemmed | A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality control |
| title_short | A simple and rapid colorimetric detection of methanol, ethanol, and isopropanol and its application toward alcohol-based hand sanitizer quality control |
| title_sort | simple and rapid colorimetric detection of methanol ethanol and isopropanol and its application toward alcohol based hand sanitizer quality control |
| topic | Alcohol Food coloring Colorimetric analysis Quick test Alcohol-based hand sanitizer |
| url | https://www.tandfonline.com/doi/10.1080/17518253.2023.2298982 |
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