Sjogren's Syndrome in the Mask of Hypokalemia: A Case Report
Sjogren's syndrome is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands resulting in xerostomia and dry eyes affecting entire body. A 40-year-old woman presented with generalized weakness and shortness of breath. She had reduced muscle power (2/5) with reduced...
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Nepal Medical Association
2024-11-01
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| Series: | Journal of Nepal Medical Association |
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| Online Access: | https://jnma.com.np/jnma/index.php/jnma/article/view/8836 |
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| author | Krishna Bahadur Sodari Pragyan Basnet Krishna Adhikari |
| author_facet | Krishna Bahadur Sodari Pragyan Basnet Krishna Adhikari |
| author_sort | Krishna Bahadur Sodari |
| collection | DOAJ |
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Sjogren's syndrome is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands resulting in xerostomia and dry eyes affecting entire body. A 40-year-old woman presented with generalized weakness and shortness of breath. She had reduced muscle power (2/5) with reduced tone, and absent reflexes in four limbs. Further investigation revealed severe hypokalemia with metabolic acidosis. She was treated with intravenous potassium chloride and diagnosed with Sjogren's syndrome based on her serology profile. After treatment, her condition improved. Hypokalemia occurs due to increased renal excretions of potassium. Distal Renal Tubular Acidosis is a major cause of potassium loss in urine. Sjogren's Syndrome is an important cause of Distal Renal Tubular Acidosis, which can present as severe hypokalemia. Although it commonly presents with symptoms like dry eyes and dry mouth, it can rarely present as Distal Renal Tubular Acidosis and hypokalemia as the primary presentation. Sjogren's syndrome should be suspected in patients with hypokalemia with features of Distal Renal Tubular Acidosis.
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| format | Article |
| id | doaj-art-ae460ba245d74e54a5a8e44e9caaa9da |
| institution | OA Journals |
| issn | 0028-2715 1815-672X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nepal Medical Association |
| record_format | Article |
| series | Journal of Nepal Medical Association |
| spelling | doaj-art-ae460ba245d74e54a5a8e44e9caaa9da2025-08-20T02:07:20ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2024-11-016228010.31729/jnma.8836Sjogren's Syndrome in the Mask of Hypokalemia: A Case ReportKrishna Bahadur Sodari0Pragyan Basnet1Krishna Adhikari2Achham District Hospital, Mangalsen, Achham, NepalBodegaun Primary Hospital, Indrawati, Sindhupalchok, NepalDepartment of Internal Medicine, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal Sjogren's syndrome is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands resulting in xerostomia and dry eyes affecting entire body. A 40-year-old woman presented with generalized weakness and shortness of breath. She had reduced muscle power (2/5) with reduced tone, and absent reflexes in four limbs. Further investigation revealed severe hypokalemia with metabolic acidosis. She was treated with intravenous potassium chloride and diagnosed with Sjogren's syndrome based on her serology profile. After treatment, her condition improved. Hypokalemia occurs due to increased renal excretions of potassium. Distal Renal Tubular Acidosis is a major cause of potassium loss in urine. Sjogren's Syndrome is an important cause of Distal Renal Tubular Acidosis, which can present as severe hypokalemia. Although it commonly presents with symptoms like dry eyes and dry mouth, it can rarely present as Distal Renal Tubular Acidosis and hypokalemia as the primary presentation. Sjogren's syndrome should be suspected in patients with hypokalemia with features of Distal Renal Tubular Acidosis. https://jnma.com.np/jnma/index.php/jnma/article/view/8836case reporthypokalemiarenal tubular acidosissjogren syndrome |
| spellingShingle | Krishna Bahadur Sodari Pragyan Basnet Krishna Adhikari Sjogren's Syndrome in the Mask of Hypokalemia: A Case Report Journal of Nepal Medical Association case report hypokalemia renal tubular acidosis sjogren syndrome |
| title | Sjogren's Syndrome in the Mask of Hypokalemia: A Case Report |
| title_full | Sjogren's Syndrome in the Mask of Hypokalemia: A Case Report |
| title_fullStr | Sjogren's Syndrome in the Mask of Hypokalemia: A Case Report |
| title_full_unstemmed | Sjogren's Syndrome in the Mask of Hypokalemia: A Case Report |
| title_short | Sjogren's Syndrome in the Mask of Hypokalemia: A Case Report |
| title_sort | sjogren s syndrome in the mask of hypokalemia a case report |
| topic | case report hypokalemia renal tubular acidosis sjogren syndrome |
| url | https://jnma.com.np/jnma/index.php/jnma/article/view/8836 |
| work_keys_str_mv | AT krishnabahadursodari sjogrenssyndromeinthemaskofhypokalemiaacasereport AT pragyanbasnet sjogrenssyndromeinthemaskofhypokalemiaacasereport AT krishnaadhikari sjogrenssyndromeinthemaskofhypokalemiaacasereport |