Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis
Objective To analyze the correlation between NT-proBNP and blood pressure variability( BPV) with the cardiovascular events in patients undergoing maintaining hemodialysis( MHD).Methods 212 patients with end-stage renal disease combined with hypertension were selected into our study from September 20...
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Editorial Department of Journal of Clinical Nephrology
2019-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57914250&Fpath=home&index=0 |
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| author | GAO Xiang SU Hua-jun DENG Liu-fen WANG Hui |
| author_facet | GAO Xiang SU Hua-jun DENG Liu-fen WANG Hui |
| author_sort | GAO Xiang |
| collection | DOAJ |
| description | Objective To analyze the correlation between NT-proBNP and blood pressure variability( BPV) with the cardiovascular events in patients undergoing maintaining hemodialysis( MHD).Methods 212 patients with end-stage renal disease combined with hypertension were selected into our study from September 2014 to September 2016. All of them received MHD at least 6 months. Ninety-one patients with cardiovascular events were assigned into the observational group and the rest 121 cases without cardiovascular events served as the controls. Clinical indexes such as age,gender,diabetes,increased rate of body weight between two times of MHD,blood biochemical indicators were analyzed. Results Univariate analyses revealed that the factors impacting the cardiovascular events included the NTproB NP levels,diabetes,increased rate of body weight between two times of MHD and SBP-SD,SBPCV,DBP-SD,DBP-CV during hemodialysis. The multivariate Logistic Regression analysis showed NTproB NP,SBP-SD and DBP-SD were the major risk factors for cardiovascular events. The ROC curve analysis revealed that the optimal cutoff of NT-proBNP,SBP-SD,DBP-SD to predict cardiovascular events was 7. 32 ng/L,21. 60 mmH g,12. 54 mmH g,respectively. Conclusions Many factors influence the cardiovascular events of MHD patients. Among them,NT-proBNP,SBP-SD,DBP-SD during hemodialysis are newly-detected and major risk factors and should be attached importance to,and have a better predictive value in cardiovascular events. |
| format | Article |
| id | doaj-art-ae3237a8e7c54eb4ac1c0cded3e9517f |
| institution | DOAJ |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2019-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-ae3237a8e7c54eb4ac1c0cded3e9517f2025-08-20T03:09:25ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902019-01-01495357914250Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysisGAO XiangSU Hua-junDENG Liu-fenWANG HuiObjective To analyze the correlation between NT-proBNP and blood pressure variability( BPV) with the cardiovascular events in patients undergoing maintaining hemodialysis( MHD).Methods 212 patients with end-stage renal disease combined with hypertension were selected into our study from September 2014 to September 2016. All of them received MHD at least 6 months. Ninety-one patients with cardiovascular events were assigned into the observational group and the rest 121 cases without cardiovascular events served as the controls. Clinical indexes such as age,gender,diabetes,increased rate of body weight between two times of MHD,blood biochemical indicators were analyzed. Results Univariate analyses revealed that the factors impacting the cardiovascular events included the NTproB NP levels,diabetes,increased rate of body weight between two times of MHD and SBP-SD,SBPCV,DBP-SD,DBP-CV during hemodialysis. The multivariate Logistic Regression analysis showed NTproB NP,SBP-SD and DBP-SD were the major risk factors for cardiovascular events. The ROC curve analysis revealed that the optimal cutoff of NT-proBNP,SBP-SD,DBP-SD to predict cardiovascular events was 7. 32 ng/L,21. 60 mmH g,12. 54 mmH g,respectively. Conclusions Many factors influence the cardiovascular events of MHD patients. Among them,NT-proBNP,SBP-SD,DBP-SD during hemodialysis are newly-detected and major risk factors and should be attached importance to,and have a better predictive value in cardiovascular events.http://www.lcszb.com/thesisDetails?columnId=57914250&Fpath=home&index=0Maintaining hemodialysisBlood pressure variabilityN-terminal probrain natriuretic peptideCardiovascular event |
| spellingShingle | GAO Xiang SU Hua-jun DENG Liu-fen WANG Hui Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis Linchuang shenzangbing zazhi Maintaining hemodialysis Blood pressure variability N-terminal probrain natriuretic peptide Cardiovascular event |
| title | Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis |
| title_full | Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis |
| title_fullStr | Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis |
| title_full_unstemmed | Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis |
| title_short | Correlation between NT-proBNP and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis |
| title_sort | correlation between nt probnp and blood pressure variability with cardiovascular events in patients undergoing maintaining hemodialysis |
| topic | Maintaining hemodialysis Blood pressure variability N-terminal probrain natriuretic peptide Cardiovascular event |
| url | http://www.lcszb.com/thesisDetails?columnId=57914250&Fpath=home&index=0 |
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