Central motor pathways involvement in patients with aseptic meningitis

Aim of our study was to investigate central motor pathways involvement in children in early recovery period after the aseptic meningitis.Materials and methods: 65 patients (40 children with average age 12 years with aseptic meningitis and 25 age matched controls) were enrolled. TMS (single-pulse pro...

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Main Authors: V. B. Voitenkov, N. V. Skripchenko, N. V. Matyunina, A. V. Klimkin
Format: Article
Language:Russian
Published: Journal Infectology 2014-09-01
Series:Журнал инфектологии
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Online Access:https://journal.niidi.ru/jofin/article/view/215
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author V. B. Voitenkov
N. V. Skripchenko
N. V. Matyunina
A. V. Klimkin
author_facet V. B. Voitenkov
N. V. Skripchenko
N. V. Matyunina
A. V. Klimkin
author_sort V. B. Voitenkov
collection DOAJ
description Aim of our study was to investigate central motor pathways involvement in children in early recovery period after the aseptic meningitis.Materials and methods: 65 patients (40 children with average age 12 years with aseptic meningitis and 25 age matched controls) were enrolled. TMS (single-pulse protocol) with MEP shape, latency and amplitude and CMCT averaged and analyzed.Results: In aseptic meningitis group in 69–73% of the patients diffuse TMS parameters changes were seen (MEPs amplitudes lowering). These changes may be interpreted as motoneurons diffuse functional activity lowering, but also as a signs of neurodegenerative process of a certain degree. Axonal lesions (MEPs latency lengthening) was registered in 12–15% of the patients of aseptic meningitis group.Conclusion. When aseptic meningitis in most cases, signs of diffuse lesion of motoneurons
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series Журнал инфектологии
spelling doaj-art-ae31c5e43cf848b09f437c9ff295f4ed2025-08-20T03:22:15ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0161192310.22625/2072-6732-2014-6-1-19-23229Central motor pathways involvement in patients with aseptic meningitisV. B. Voitenkov0N. V. Skripchenko1N. V. Matyunina2A. V. Klimkin3Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, RussiaностиScience Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, RussiaностиScience Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, RussiaностиScience Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, RussiaностиAim of our study was to investigate central motor pathways involvement in children in early recovery period after the aseptic meningitis.Materials and methods: 65 patients (40 children with average age 12 years with aseptic meningitis and 25 age matched controls) were enrolled. TMS (single-pulse protocol) with MEP shape, latency and amplitude and CMCT averaged and analyzed.Results: In aseptic meningitis group in 69–73% of the patients diffuse TMS parameters changes were seen (MEPs amplitudes lowering). These changes may be interpreted as motoneurons diffuse functional activity lowering, but also as a signs of neurodegenerative process of a certain degree. Axonal lesions (MEPs latency lengthening) was registered in 12–15% of the patients of aseptic meningitis group.Conclusion. When aseptic meningitis in most cases, signs of diffuse lesion of motoneuronshttps://journal.niidi.ru/jofin/article/view/215aseptic meningitistranscranial magnetic stimulationearly recovery periodmotor pathwaysneurodegeneration
spellingShingle V. B. Voitenkov
N. V. Skripchenko
N. V. Matyunina
A. V. Klimkin
Central motor pathways involvement in patients with aseptic meningitis
Журнал инфектологии
aseptic meningitis
transcranial magnetic stimulation
early recovery period
motor pathways
neurodegeneration
title Central motor pathways involvement in patients with aseptic meningitis
title_full Central motor pathways involvement in patients with aseptic meningitis
title_fullStr Central motor pathways involvement in patients with aseptic meningitis
title_full_unstemmed Central motor pathways involvement in patients with aseptic meningitis
title_short Central motor pathways involvement in patients with aseptic meningitis
title_sort central motor pathways involvement in patients with aseptic meningitis
topic aseptic meningitis
transcranial magnetic stimulation
early recovery period
motor pathways
neurodegeneration
url https://journal.niidi.ru/jofin/article/view/215
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AT nvmatyunina centralmotorpathwaysinvolvementinpatientswithasepticmeningitis
AT avklimkin centralmotorpathwaysinvolvementinpatientswithasepticmeningitis