Reprogramming of liver metabolism during West Nile virus infection unveils novel aspects of disease pathophysiology

Reprogramming of liver metabolism during West Nile virus infection unveils novel aspects of disease pathophysiology

Abstract Background West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus responsible for outbreaks of encephalitis and meningitis worldwide. About 20% of infected patients exhibit abnormal liver function tests, although the participation of this organ in the pathophysiology of the diseas...

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Bibliographic Details
Main Authors: Patricia Mingo-Casas, Ana-Belén Blázquez, Josefina Casas, Ana Esteban, Estela Escribano-Romero, Pedro J. Sánchez-Cordón, Nereida Jiménez de Oya, Juan-Carlos Saiz, Miguel A. Martín-Acebes
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Medicine
Subjects:
West Nile virus
Infection
Metabolism
Glutathione
Lipid
Lipid droplet
Online Access:https://doi.org/10.1186/s10020-025-01300-8
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