The health-related quality of life in children with IgA vasculitis
IntroductionThe objective of this study was to investigate the health-related quality of life (HRQOL) in children diagnosed with IgAV and explore factors influencing it, aiming to provide insights for rehabilitation of these children.MethodsThis study enrolled 114 children diagnosed with IgAV at Baz...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1534687/full |
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| author | Juan Zhou Juan Zhou Min Nie Zixia Song Xing Shen |
| author_facet | Juan Zhou Juan Zhou Min Nie Zixia Song Xing Shen |
| author_sort | Juan Zhou |
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| description | IntroductionThe objective of this study was to investigate the health-related quality of life (HRQOL) in children diagnosed with IgAV and explore factors influencing it, aiming to provide insights for rehabilitation of these children.MethodsThis study enrolled 114 children diagnosed with IgAV at Bazhong Central Hospital between January 2019 and January 2023. 51 healthy children undergoing health check-ups during the same period were enrolled in control group. Data on sociodemographic and clinical characteristics, as well as health-related quality of life scores, were collected. The Pediatric Quality of Life Inventory Measurement Models 4.0 (PedsQL™ 4.0) was utilized to assess the HRQOL of these children and to explore correlations among different dimensions of quality of life. General linear regression models were applied to analysis of influencing factors of the HRQOL of children with IgAV.ResultsThe health-related quality of life scores in all dimensions for children with IgAV were lower compared to those of healthy children. Recurrence of IgAV was negatively correlated with all dimension scores and the total HRQOL score (P < 0.05). Children with exercise-induced onset showed lower physiological functioning scores compared to those without exercise-induced onset. Emotional functioning scores were lower in children with self-funded medical care compared to those with Medicare. Children with medication duration longer than 1 week exhibited higher social functioning scores.ConclusionsThe HRQOL of IgAV children is lower than that of healthy children. Relapse, exercise, the payment method and regularity of medications affect children's health-related quality of life. |
| format | Article |
| id | doaj-art-ae208970dde34370aa65012d0823c351 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Pediatrics |
| spelling | doaj-art-ae208970dde34370aa65012d0823c3512025-08-20T03:49:42ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-05-011310.3389/fped.2025.15346871534687The health-related quality of life in children with IgA vasculitisJuan Zhou0Juan Zhou1Min Nie2Zixia Song3Xing Shen4Department of Pediatrics, Bazhong Central Hospital, Bazhong, Sichuan, ChinaDepartment of Pediatrics, SichuanClinical Research Center for Birth Defects, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, ChinaDepartment of Pediatrics, SichuanClinical Research Center for Birth Defects, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, ChinaDepartment of Pediatrics, NanChong Central Hospital, NanChong, Sichuan, ChinaDepartment of Pediatrics, SichuanClinical Research Center for Birth Defects, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, ChinaIntroductionThe objective of this study was to investigate the health-related quality of life (HRQOL) in children diagnosed with IgAV and explore factors influencing it, aiming to provide insights for rehabilitation of these children.MethodsThis study enrolled 114 children diagnosed with IgAV at Bazhong Central Hospital between January 2019 and January 2023. 51 healthy children undergoing health check-ups during the same period were enrolled in control group. Data on sociodemographic and clinical characteristics, as well as health-related quality of life scores, were collected. The Pediatric Quality of Life Inventory Measurement Models 4.0 (PedsQL™ 4.0) was utilized to assess the HRQOL of these children and to explore correlations among different dimensions of quality of life. General linear regression models were applied to analysis of influencing factors of the HRQOL of children with IgAV.ResultsThe health-related quality of life scores in all dimensions for children with IgAV were lower compared to those of healthy children. Recurrence of IgAV was negatively correlated with all dimension scores and the total HRQOL score (P < 0.05). Children with exercise-induced onset showed lower physiological functioning scores compared to those without exercise-induced onset. Emotional functioning scores were lower in children with self-funded medical care compared to those with Medicare. Children with medication duration longer than 1 week exhibited higher social functioning scores.ConclusionsThe HRQOL of IgAV children is lower than that of healthy children. Relapse, exercise, the payment method and regularity of medications affect children's health-related quality of life.https://www.frontiersin.org/articles/10.3389/fped.2025.1534687/fullhealth-related quality of lifeIgA vasculitischildrenPedsQLTM 4.0recurrence |
| spellingShingle | Juan Zhou Juan Zhou Min Nie Zixia Song Xing Shen The health-related quality of life in children with IgA vasculitis Frontiers in Pediatrics health-related quality of life IgA vasculitis children PedsQLTM 4.0 recurrence |
| title | The health-related quality of life in children with IgA vasculitis |
| title_full | The health-related quality of life in children with IgA vasculitis |
| title_fullStr | The health-related quality of life in children with IgA vasculitis |
| title_full_unstemmed | The health-related quality of life in children with IgA vasculitis |
| title_short | The health-related quality of life in children with IgA vasculitis |
| title_sort | health related quality of life in children with iga vasculitis |
| topic | health-related quality of life IgA vasculitis children PedsQLTM 4.0 recurrence |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1534687/full |
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