Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysis
The development and synthesis of notably targeted and colorimetric sensor based on an azomethine compound for the distinct recognition of Cu2+ and CN− ion individually in an aqueous dimethyl formamide solution is performed. In the presence of CN− and Cu2+, the sensor BTZ showed impressive colorimetr...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-10-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024146245 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850194453849964544 |
|---|---|
| author | P.S. Umabharathi S. Karpagam Tiasha Dasgupta Ramasamy Tamizhselvi |
| author_facet | P.S. Umabharathi S. Karpagam Tiasha Dasgupta Ramasamy Tamizhselvi |
| author_sort | P.S. Umabharathi |
| collection | DOAJ |
| description | The development and synthesis of notably targeted and colorimetric sensor based on an azomethine compound for the distinct recognition of Cu2+ and CN− ion individually in an aqueous dimethyl formamide solution is performed. In the presence of CN− and Cu2+, the sensor BTZ showed impressive colorimetric changes, going from pale yellow to orange and pale yellow to dark yellow, respectively. In the meantime, FL spectrum (Cu2+) and UV–vis spectroscopy (CN−/Cu2+) were used to assess the sensing features. The plausible binding mechanisms of CN− and Cu2+ ions with sensor BTZ have been studied using the 1H NMR titration, Job's plot and DFT technique. The bathochromic shift produced by the intramolecular charge transfer (ICT) transition may have been the source of the phenomenon. Furthermore, CN− ion in the commercial substance is quickly identified and measured with the naked eye by using sensor BTZ. It was found that the BTZ's LOD for CN− and Cu2+ was 0.280 × 10−7 M and 1.153 × 10−7 M, respectively. Moreover, 1:1 binding ratio for the reaction of CN− and Cu2+ ions with sensor BTZ were demonstrated by Job's plot, which was dependent on analytical data. The findings show that BTZ is an easy-to-use and practical probe for concurrently sensing cyanide and copper ions in environmental samples and living cells that have less cytotoxicity. |
| format | Article |
| id | doaj-art-ae1e2935d2524dbca9eccbb2a9720b22 |
| institution | OA Journals |
| issn | 2405-8440 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-ae1e2935d2524dbca9eccbb2a9720b222025-08-20T02:13:59ZengElsevierHeliyon2405-84402024-10-011020e3859310.1016/j.heliyon.2024.e38593Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysisP.S. Umabharathi0S. Karpagam1Tiasha Dasgupta2Ramasamy Tamizhselvi3Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 14, Tamil Nadu, IndiaDepartment of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 14, Tamil Nadu, India; Corresponding author.School of Bio Science and Technology, Vellore Institute of Technology, Vellore, 14, Tamilnadu, IndiaSchool of Bio Science and Technology, Vellore Institute of Technology, Vellore, 14, Tamilnadu, IndiaThe development and synthesis of notably targeted and colorimetric sensor based on an azomethine compound for the distinct recognition of Cu2+ and CN− ion individually in an aqueous dimethyl formamide solution is performed. In the presence of CN− and Cu2+, the sensor BTZ showed impressive colorimetric changes, going from pale yellow to orange and pale yellow to dark yellow, respectively. In the meantime, FL spectrum (Cu2+) and UV–vis spectroscopy (CN−/Cu2+) were used to assess the sensing features. The plausible binding mechanisms of CN− and Cu2+ ions with sensor BTZ have been studied using the 1H NMR titration, Job's plot and DFT technique. The bathochromic shift produced by the intramolecular charge transfer (ICT) transition may have been the source of the phenomenon. Furthermore, CN− ion in the commercial substance is quickly identified and measured with the naked eye by using sensor BTZ. It was found that the BTZ's LOD for CN− and Cu2+ was 0.280 × 10−7 M and 1.153 × 10−7 M, respectively. Moreover, 1:1 binding ratio for the reaction of CN− and Cu2+ ions with sensor BTZ were demonstrated by Job's plot, which was dependent on analytical data. The findings show that BTZ is an easy-to-use and practical probe for concurrently sensing cyanide and copper ions in environmental samples and living cells that have less cytotoxicity.http://www.sciencedirect.com/science/article/pii/S2405844024146245MultifunctionalCyanide ionCopper ionColorimetricAzomethineSensing tool |
| spellingShingle | P.S. Umabharathi S. Karpagam Tiasha Dasgupta Ramasamy Tamizhselvi Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysis Heliyon Multifunctional Cyanide ion Copper ion Colorimetric Azomethine Sensing tool |
| title | Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysis |
| title_full | Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysis |
| title_fullStr | Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysis |
| title_full_unstemmed | Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysis |
| title_short | Benzothiazole-quinoline based probe for simultaneous colorimetric detection of CN- and Cu2+ ions, with fluorescence sensing for Cu2+: Mechanistic insights and practical applications in environmental monitoring and cellular analysis |
| title_sort | benzothiazole quinoline based probe for simultaneous colorimetric detection of cn and cu2 ions with fluorescence sensing for cu2 mechanistic insights and practical applications in environmental monitoring and cellular analysis |
| topic | Multifunctional Cyanide ion Copper ion Colorimetric Azomethine Sensing tool |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024146245 |
| work_keys_str_mv | AT psumabharathi benzothiazolequinolinebasedprobeforsimultaneouscolorimetricdetectionofcnandcu2ionswithfluorescencesensingforcu2mechanisticinsightsandpracticalapplicationsinenvironmentalmonitoringandcellularanalysis AT skarpagam benzothiazolequinolinebasedprobeforsimultaneouscolorimetricdetectionofcnandcu2ionswithfluorescencesensingforcu2mechanisticinsightsandpracticalapplicationsinenvironmentalmonitoringandcellularanalysis AT tiashadasgupta benzothiazolequinolinebasedprobeforsimultaneouscolorimetricdetectionofcnandcu2ionswithfluorescencesensingforcu2mechanisticinsightsandpracticalapplicationsinenvironmentalmonitoringandcellularanalysis AT ramasamytamizhselvi benzothiazolequinolinebasedprobeforsimultaneouscolorimetricdetectionofcnandcu2ionswithfluorescencesensingforcu2mechanisticinsightsandpracticalapplicationsinenvironmentalmonitoringandcellularanalysis |