Turnover of Focal Adhesions and Cancer Cell Migration
Cells are usually surrounded by the extracellular matrix (ECM), and adhesion of the cells to the ECM is a key step in their migration through tissues. Integrins are important receptors for the ECM and form structures called focal adhesions (FAs). Formation and disassembly of FAs are regulated dynami...
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Main Authors: | Makoto Nagano, Daisuke Hoshino, Naohiko Koshikawa, Toshifumi Akizawa, Motoharu Seiki |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2012/310616 |
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