Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report
Patients with advanced endometrial cancer had generally a poor prognostic with a median survival often less than one year. Isolated bone metastases as the first sign of the disease of endometrial cancer was a very exceptional situation rarely described in the literature. The goal of this report is...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Medical Network
2022-03-01
|
| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/1191 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823857370438041600 |
|---|---|
| author | Nesrine Tounsi Ines Zemni Fatma Saadalah Maher Slimane Nadia Boujelbene Mohamed ali Ayadi Chargui Rhiad Rahal Khaled |
| author_facet | Nesrine Tounsi Ines Zemni Fatma Saadalah Maher Slimane Nadia Boujelbene Mohamed ali Ayadi Chargui Rhiad Rahal Khaled |
| author_sort | Nesrine Tounsi |
| collection | DOAJ |
| description |
Patients with advanced endometrial cancer had generally a poor prognostic with a median survival often less than one year. Isolated bone metastases as the first sign of the disease of endometrial cancer was a very exceptional situation rarely described in the literature. The goal of this report is to describe the management of this rare site of metastases and to reviewed Clinic pathological features and prognosis of isolated bone metastases. We present a case of a 56-year-old woman treated for endometrial cancer with isolated ribs bone metastases. She was complaining about progressive right rib pain as a first sign of the disease of endometrial cancer. She had a biopsy of the lesion in the last right thoracic rib. This has proved a metastatic adenocarcinoma compatible with an endometrial primary cancer. An endometrial biopsy showed moderately differentiated endometrioid adenocarcinoma. Imagery did not reveal any other sites of metastatic disease. The patient underwent bilateral salpingo-oophorectomy and hysterectomy, peritoneal washing, omentectomy, bilateral pelvic and par aortic lymphadenectomy. In addition, a right thoracotomy was carried out and complete surgical excision of the rib mass was successfully performed. Adjuvant chemotherapy was administrated. The patient is clinically free of disease 10 months following diagnosis. Single-bone extrauterine metastatic site and local disease limited to the uterus had better survival outcomes than Stage IVb endometrial cancer with multiple metastatic sites. Therefore, the patient treated with surgery with a clear margin continued to behave as early-stage endometrial cancer.
|
| format | Article |
| id | doaj-art-ae0ac800bdd74283881f36a4e9a5f395 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-ae0ac800bdd74283881f36a4e9a5f3952025-02-11T21:14:41ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182022-03-0128110.21613/GORM.2021.1191Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case ReportNesrine Tounsi0Ines Zemni1Fatma Saadalah2Maher Slimane3Nadia Boujelbene4Mohamed ali Ayadi5Chargui Rhiad6Rahal Khaled7Department of Surgical oncologists, Salah-Azaiez institute, boulevard of 9-Avril, 1001 Tunis, Tunisia.Department of surgical oncology, Salah Azaiz Institute, University Tunis El Manar, Tunis, Tunisia.Department of surgical oncology, Salah Azaiz Institute, University Tunis El Manar, Tunis, Tunisia.Department of surgical oncology, Salah Azaiz Institute, University Tunis El Manar, Tunis, Tunisia.²Department of Pathology, Salah Azaiz Institute, University Tunis El Manar Tunis, Tunisia.Department of surgical oncology, Salah Azaiz Institute, University Tunis El Manar, Tunis, Tunisia.Department of surgical oncology, Salah Azaiz Institute, University Tunis El Manar, Tunis, Tunisia.Department of surgical oncology, Salah Azaiz Institute, University Tunis El Manar, Tunis, Tunisia. Patients with advanced endometrial cancer had generally a poor prognostic with a median survival often less than one year. Isolated bone metastases as the first sign of the disease of endometrial cancer was a very exceptional situation rarely described in the literature. The goal of this report is to describe the management of this rare site of metastases and to reviewed Clinic pathological features and prognosis of isolated bone metastases. We present a case of a 56-year-old woman treated for endometrial cancer with isolated ribs bone metastases. She was complaining about progressive right rib pain as a first sign of the disease of endometrial cancer. She had a biopsy of the lesion in the last right thoracic rib. This has proved a metastatic adenocarcinoma compatible with an endometrial primary cancer. An endometrial biopsy showed moderately differentiated endometrioid adenocarcinoma. Imagery did not reveal any other sites of metastatic disease. The patient underwent bilateral salpingo-oophorectomy and hysterectomy, peritoneal washing, omentectomy, bilateral pelvic and par aortic lymphadenectomy. In addition, a right thoracotomy was carried out and complete surgical excision of the rib mass was successfully performed. Adjuvant chemotherapy was administrated. The patient is clinically free of disease 10 months following diagnosis. Single-bone extrauterine metastatic site and local disease limited to the uterus had better survival outcomes than Stage IVb endometrial cancer with multiple metastatic sites. Therefore, the patient treated with surgery with a clear margin continued to behave as early-stage endometrial cancer. https://gorm.com.tr/index.php/GORM/article/view/1191Bone metastasisChemotherapyEndometrial cancerIsolated metastasisRib |
| spellingShingle | Nesrine Tounsi Ines Zemni Fatma Saadalah Maher Slimane Nadia Boujelbene Mohamed ali Ayadi Chargui Rhiad Rahal Khaled Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report Gynecology Obstetrics & Reproductive Medicine Bone metastasis Chemotherapy Endometrial cancer Isolated metastasis Rib |
| title | Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report |
| title_full | Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report |
| title_fullStr | Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report |
| title_full_unstemmed | Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report |
| title_short | Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report |
| title_sort | endometrial carcinoma presenting with an isolated osseous metastasis a case report |
| topic | Bone metastasis Chemotherapy Endometrial cancer Isolated metastasis Rib |
| url | https://gorm.com.tr/index.php/GORM/article/view/1191 |
| work_keys_str_mv | AT nesrinetounsi endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport AT ineszemni endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport AT fatmasaadalah endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport AT maherslimane endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport AT nadiaboujelbene endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport AT mohamedaliayadi endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport AT charguirhiad endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport AT rahalkhaled endometrialcarcinomapresentingwithanisolatedosseousmetastasisacasereport |