STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR

In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of...

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Format: Article
Language:English
Published: University of Tehran 1991-12-01
Series:Journal of Sciences, Islamic Republic of Iran
Online Access:https://jsciences.ut.ac.ir/article_31438_6b262b24bf6da88e4cacff457c2b94e3.pdf
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description In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both rabbit and guinea pig lung tissues produced and released CSF in the conditioned medium. The CSFs were active on ammonium chloride treated bone marrow cells from balblc mouse and on their own ammonium chloride treated bone marrow cells but could not stimulate the progenitor cells from other sources
format Article
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institution OA Journals
issn 1016-1104
2345-6914
language English
publishDate 1991-12-01
publisher University of Tehran
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series Journal of Sciences, Islamic Republic of Iran
spelling doaj-art-adff09ff98f449e38410a220bd0e70d22025-08-20T01:53:31ZengUniversity of TehranJournal of Sciences, Islamic Republic of Iran1016-11042345-69141991-12-012231438STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTORIn this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both rabbit and guinea pig lung tissues produced and released CSF in the conditioned medium. The CSFs were active on ammonium chloride treated bone marrow cells from balblc mouse and on their own ammonium chloride treated bone marrow cells but could not stimulate the progenitor cells from other sourceshttps://jsciences.ut.ac.ir/article_31438_6b262b24bf6da88e4cacff457c2b94e3.pdf
spellingShingle STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR
Journal of Sciences, Islamic Republic of Iran
title STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR
title_full STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR
title_fullStr STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR
title_full_unstemmed STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR
title_short STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR
title_sort studies on the tissue specificity of colony stimulating factor
url https://jsciences.ut.ac.ir/article_31438_6b262b24bf6da88e4cacff457c2b94e3.pdf