Roles of VWA1 and Rac2 in compensatory and decompensatory responses via FGF9/FGFR3 and p38 MAPK signaling pathways in condylar chondrocytes under distinct mechanical stress

Abstract Background/purpose Few studies paid attention to compensatory and decompensatory responses of condylar cartilage under different mechanical conditions and the underlying mechanism. Materials and methods Compensatory and decompensatory models were established. In vivo compensatory (0.5 mm oc...

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Bibliographic Details
Main Authors: Yuqi Liu, Fangwen Jia, Kangya Li, Chao Liang, Yanxi Li, Wei Geng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-025-03579-8
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