Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone
Severe COVID-19 infection management for a recipient of kidney transplant has debatable prognosis and treatment. We described the case of a COVID-19 infected 70 year old female, previously had renal transplantation in 2017. The patient took immunosuppressive agents as routine drugs for transplant r...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2021-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/14952 |
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| author | Satriyo Dwi Suryantoro Mochammad Thaha Pranawa Djoko Santoso Nunuk Mardiana Widodo Aditiawardana Artaria Tjempakasari Ardityo Rahmat Ardhany Dana Pramudya Decsa Medika Hertanto Evy Febriane Meryana Maria Angela Ari Christy Muliono Handoko Tanuwidjaja Philia Setiawan David Sugiarto |
| author_facet | Satriyo Dwi Suryantoro Mochammad Thaha Pranawa Djoko Santoso Nunuk Mardiana Widodo Aditiawardana Artaria Tjempakasari Ardityo Rahmat Ardhany Dana Pramudya Decsa Medika Hertanto Evy Febriane Meryana Maria Angela Ari Christy Muliono Handoko Tanuwidjaja Philia Setiawan David Sugiarto |
| author_sort | Satriyo Dwi Suryantoro |
| collection | DOAJ |
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Severe COVID-19 infection management for a recipient of kidney transplant has debatable prognosis and treatment. We described the case of a COVID-19 infected 70 year old female, previously had renal transplantation in 2017. The patient took immunosuppressive agents as routine drugs for transplant recipient status and received lopinavir/ritonavir, hydroxychloroquine, and dexamethasone daily at the hospitalization. Specific question arises about renal transplant recipients being infected by COVID-19 – whether the infection will get worse compared to those without immunosuppresive agent. In this case, author decided to stop the immunosuppressive agent followed administration of combination lopinavir/ritonavir, hydroxychloroquine, and dexamethasone that gives a good clinical impact change to patient’s condition after once getting worsened and mechanically ventilated. Nevertheless, the assessment of risk and benefit in continuing immunosuppressive drugs is concurrently essential due to the prevention of transplant rejection.
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| format | Article |
| id | doaj-art-adf688467f094da2b1454162e9b1be61 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2021-09-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-adf688467f094da2b1454162e9b1be612025-08-20T03:52:39ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802021-09-01150910.3855/jidc.14952Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasoneSatriyo Dwi Suryantoro0Mochammad Thaha1Pranawa2Djoko Santoso3Nunuk Mardiana4Widodo5Aditiawardana6Artaria Tjempakasari7Ardityo Rahmat Ardhany8Dana Pramudya9Decsa Medika Hertanto10Evy Febriane11Meryana12Maria Angela13Ari Christy Muliono14Handoko Tanuwidjaja15Philia Setiawan16David Sugiarto17Department of Internal Medicine, Faculty of Medicine Airlangga University, Airlangga University Hospital, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, Airlangga University Hospital, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Airlangga University, General Teaching Hospital Dr. Soetomo, Surabaya, IndonesiaPremier Hospital Surabaya, Surabaya, IndonesiaPremier Hospital Surabaya, Surabaya, IndonesiaPremier Hospital Surabaya, Surabaya, IndonesiaPremier Hospital Surabaya, Surabaya, IndonesiaPremier Hospital Surabaya, Surabaya, IndonesiaPremier Hospital Surabaya, Surabaya, IndonesiaPremier Hospital Surabaya, Surabaya, Indonesia Severe COVID-19 infection management for a recipient of kidney transplant has debatable prognosis and treatment. We described the case of a COVID-19 infected 70 year old female, previously had renal transplantation in 2017. The patient took immunosuppressive agents as routine drugs for transplant recipient status and received lopinavir/ritonavir, hydroxychloroquine, and dexamethasone daily at the hospitalization. Specific question arises about renal transplant recipients being infected by COVID-19 – whether the infection will get worse compared to those without immunosuppresive agent. In this case, author decided to stop the immunosuppressive agent followed administration of combination lopinavir/ritonavir, hydroxychloroquine, and dexamethasone that gives a good clinical impact change to patient’s condition after once getting worsened and mechanically ventilated. Nevertheless, the assessment of risk and benefit in continuing immunosuppressive drugs is concurrently essential due to the prevention of transplant rejection. https://jidc.org/index.php/journal/article/view/14952kidney transplantimmunosupressive drugslopinavirritonavirhydroxycholorquine |
| spellingShingle | Satriyo Dwi Suryantoro Mochammad Thaha Pranawa Djoko Santoso Nunuk Mardiana Widodo Aditiawardana Artaria Tjempakasari Ardityo Rahmat Ardhany Dana Pramudya Decsa Medika Hertanto Evy Febriane Meryana Maria Angela Ari Christy Muliono Handoko Tanuwidjaja Philia Setiawan David Sugiarto Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone Journal of Infection in Developing Countries kidney transplant immunosupressive drugs lopinavir ritonavir hydroxycholorquine |
| title | Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone |
| title_full | Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone |
| title_fullStr | Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone |
| title_full_unstemmed | Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone |
| title_short | Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone |
| title_sort | severe covid 19 infection in a kidney transplant recipient treated with lopinavir ritonavir hydroxychloroquine and dexamethasone |
| topic | kidney transplant immunosupressive drugs lopinavir ritonavir hydroxycholorquine |
| url | https://jidc.org/index.php/journal/article/view/14952 |
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