Significance of immunophenotypic, cytogenetic, and molecular markers in adult patients with T-cell lymphoblastic leukemia

Significance of immunophenotypic, cytogenetic, and molecular markers in adult patients with T-cell lymphoblastic leukemia

Background. Current chemotherapy protocols for T-cell acute lymphoblastic leukemia (T-ALL) allow achieving a 5-year overall survival of 60–90 %, but relapsed and refractory forms remain incurable situations.Aim. To determine the significance of immunophenotypic, cytogenetic and molecular markers in...

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Bibliographic Details
Main Authors: A. N. Vasileva, O. A. Aleshina, E. S. Kotova, B. V. Biderman, T. N. Obukhova, I. V. Galtseva, V. N. Dvirnyk, E. I. Zakharko, A. B. Sudarikov, E. N. Parovichnikova
Format: Article
Language:Russian
Published: ABV-press 2024-04-01
Series:Онкогематология
Subjects:
acute lymphoblastic leukemia
minimal residual disease
cytogenetic anomalies
molecular profile
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/920
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