BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION
Objective: Mechanical dilatation and adjuvant injection of triamcinolone acetate (TA) effectively preserve the opening provided and reduce the number of bougie dilation (BD) in benign esophageal strictures. In this study, we aimed to evaluate the role of Methylprednisolone (MP) injection after BD in...
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Istanbul University Press
2022-07-01
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| Series: | İstanbul Tıp Fakültesi Dergisi |
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| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/15D3CB2ECD924DB292A51609A2163692 |
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| author | İbrahim Hakkı Köker Hakan Şentürk |
| author_facet | İbrahim Hakkı Köker Hakan Şentürk |
| author_sort | İbrahim Hakkı Köker |
| collection | DOAJ |
| description | Objective: Mechanical dilatation and adjuvant injection of triamcinolone acetate (TA) effectively preserve the opening provided and reduce the number of bougie dilation (BD) in benign esophageal strictures. In this study, we aimed to evaluate the role of Methylprednisolone (MP) injection after BD in providing permanent/long-term lumen opening. Materials and Methods: Among 22 patients diagnosed with benign esophageal strictures (BES) between January 2017 and October 2020, we evaluated the results of 8 patients who continued the endoscopic follow-up program and underwent BD and MP injection, then compared with the literature. Results: We treated 8 patients [6 (75%) women, mean age 61±16.9 years (range 22-77)] with strictures of different etiologies (3 anastomotic, 2 iatrogenic esophageal rupture repairs, 2 recurrent webs, and 1 scleroderma) with BD followed by intralesional MP injection. We performed median BD sessions 3.5 times (range 1-8). We gave a median 3 intralesional MP injection (range 1-7). The median time to resolve stricture was 2.5 months (range 1-4). The median endoscopic follow-up time was 4.5 months (range 1-17). Conclusions: Adjuvant MP injection is successful in preserving the lumen patency provided after mechanical dilatation. Randomized controlled studies are needed to determine the steroid type and dose to provide the most optimal permanent lumen opening with lesser dilatation sessions in BES. |
| format | Article |
| id | doaj-art-adebee30c5244a89ab030d0e140ba2a1 |
| institution | OA Journals |
| issn | 1305-6441 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | Istanbul University Press |
| record_format | Article |
| series | İstanbul Tıp Fakültesi Dergisi |
| spelling | doaj-art-adebee30c5244a89ab030d0e140ba2a12025-08-20T02:15:19ZengIstanbul University Pressİstanbul Tıp Fakültesi Dergisi1305-64412022-07-0185330531110.26650/IUITFD.1011641123456BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTIONİbrahim Hakkı Köker0https://orcid.org/0000-0002-4513-6927Hakan Şentürk1https://orcid.org/0000-0002-2440-4478Bezmiâlem Vakıf Üniversitesi, Istanbul, TurkiyeBezmiâlem Vakıf Üniversitesi, Istanbul, TurkiyeObjective: Mechanical dilatation and adjuvant injection of triamcinolone acetate (TA) effectively preserve the opening provided and reduce the number of bougie dilation (BD) in benign esophageal strictures. In this study, we aimed to evaluate the role of Methylprednisolone (MP) injection after BD in providing permanent/long-term lumen opening. Materials and Methods: Among 22 patients diagnosed with benign esophageal strictures (BES) between January 2017 and October 2020, we evaluated the results of 8 patients who continued the endoscopic follow-up program and underwent BD and MP injection, then compared with the literature. Results: We treated 8 patients [6 (75%) women, mean age 61±16.9 years (range 22-77)] with strictures of different etiologies (3 anastomotic, 2 iatrogenic esophageal rupture repairs, 2 recurrent webs, and 1 scleroderma) with BD followed by intralesional MP injection. We performed median BD sessions 3.5 times (range 1-8). We gave a median 3 intralesional MP injection (range 1-7). The median time to resolve stricture was 2.5 months (range 1-4). The median endoscopic follow-up time was 4.5 months (range 1-17). Conclusions: Adjuvant MP injection is successful in preserving the lumen patency provided after mechanical dilatation. Randomized controlled studies are needed to determine the steroid type and dose to provide the most optimal permanent lumen opening with lesser dilatation sessions in BES.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/15D3CB2ECD924DB292A51609A2163692benign esophageal stricturebougie dilationendoscopic therapymethylprednisolone |
| spellingShingle | İbrahim Hakkı Köker Hakan Şentürk BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION İstanbul Tıp Fakültesi Dergisi benign esophageal stricture bougie dilation endoscopic therapy methylprednisolone |
| title | BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION |
| title_full | BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION |
| title_fullStr | BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION |
| title_full_unstemmed | BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION |
| title_short | BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION |
| title_sort | bougie dilatation in benign esophageal strictures evaluation of adjuvant methylprednisolone injection |
| topic | benign esophageal stricture bougie dilation endoscopic therapy methylprednisolone |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/15D3CB2ECD924DB292A51609A2163692 |
| work_keys_str_mv | AT ibrahimhakkıkoker bougiedilatationinbenignesophagealstricturesevaluationofadjuvantmethylprednisoloneinjection AT hakansenturk bougiedilatationinbenignesophagealstricturesevaluationofadjuvantmethylprednisoloneinjection |