[Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective study
Objective: To determine if subchondral bone damage can influence the clinical results of intraarticular platelet-rich-plasma (PRP) treatment in knee osteoarthritic patients. Material and methods: A retrospective review of patients treated with intraarticular PRP injections for knee osteoarthritis wh...
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Elsevier
2025-03-01
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| Series: | Revista Española de Cirugía Ortopédica y Traumatología |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1888441524002054 |
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| author | R. Escribano Rey |
| author_facet | R. Escribano Rey |
| author_sort | R. Escribano Rey |
| collection | DOAJ |
| description | Objective: To determine if subchondral bone damage can influence the clinical results of intraarticular platelet-rich-plasma (PRP) treatment in knee osteoarthritic patients. Material and methods: A retrospective review of patients treated with intraarticular PRP injections for knee osteoarthritis who previously underwent a magnetic resonance (MR) of the knee was performed. Visual Analogic Score (VAS) was assessed for pain, whereas WORMS MR score was adapted to assess the damage to the subchondral bone (WORMSsc score). Results: Sixty-one patients were treated with 3 weekly injections of PRP. Mean VAS reduction was 27.67 ± 13.13 points (p < .005). WORMS sc mean score was 32 ± 18.5 points. No correlation between WORMSsc and VAS was found. A moderate correlation between WORMSsc score and preoperative VAS was found (r = .43; p < .005). Conclusion: There is no correlation between the damage to the subchondral bone assessed by MR and pain relief at 12 weeks in patients treated with intraarticular platelet-rich plasma in patients with knee osteoarthritis. A greater damage to the subchondral bone could be associated with more pain. Resumen: Objetivo: Determinar si las lesiones en el hueso subcondral en la artrosis de rodilla pueden condicionar el resultado del tratamiento con plasma rico en plaquetas (PRP) intraarticular. Material y métodos: Se revisó retrospectivamente a los pacientes con artrosis de rodilla tratados con PRP intraarticular sometidos previamente a una resonancia magnética (RM). Se evaluó la escala visual analógica (EVA) y las imágenes de resonancia mediante una adaptación de la escala WORMS graduando el daño al hueso subcondral (WORMSsc). Resultados: Se estudiaron 61 pacientes tratados con PRP intraarticular en 3 sesiones. Se obtuvo una mejoría en la escala EVA de 27,67 ± 13,13 puntos (p < 0,005). La puntuación de los ítems de la escala WORMSsc fue de 32 ± 18,5 puntos, no encontrándose correlación con la escala EVA. Se encontró una correlación moderada (r = 0,43; p < 0,005) entre la escala WORMSsc y la escala EVA pretratamiento. Conclusiones: No existe correlación entre el resultado clínico a las 12 semanas y el daño del hueso subcondral evaluado mediante RM en los pacientes con artrosis de rodilla tratados con PRP intraarticular. Un mayor daño del hueso subcondral podría estar asociado con mayor dolor. |
| format | Article |
| id | doaj-art-adea511309bc4182bfeae92d009814e2 |
| institution | DOAJ |
| issn | 1888-4415 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Española de Cirugía Ortopédica y Traumatología |
| spelling | doaj-art-adea511309bc4182bfeae92d009814e22025-08-20T03:16:26ZengElsevierRevista Española de Cirugía Ortopédica y Traumatología1888-44152025-03-01692T183T18910.1016/j.recot.2024.11.020[Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective studyR. Escribano Rey0Servicio de Cirugía Ortopédica y Traumatología, Hospital de Calahorra, Calahorra, La Rioja, SpainObjective: To determine if subchondral bone damage can influence the clinical results of intraarticular platelet-rich-plasma (PRP) treatment in knee osteoarthritic patients. Material and methods: A retrospective review of patients treated with intraarticular PRP injections for knee osteoarthritis who previously underwent a magnetic resonance (MR) of the knee was performed. Visual Analogic Score (VAS) was assessed for pain, whereas WORMS MR score was adapted to assess the damage to the subchondral bone (WORMSsc score). Results: Sixty-one patients were treated with 3 weekly injections of PRP. Mean VAS reduction was 27.67 ± 13.13 points (p < .005). WORMS sc mean score was 32 ± 18.5 points. No correlation between WORMSsc and VAS was found. A moderate correlation between WORMSsc score and preoperative VAS was found (r = .43; p < .005). Conclusion: There is no correlation between the damage to the subchondral bone assessed by MR and pain relief at 12 weeks in patients treated with intraarticular platelet-rich plasma in patients with knee osteoarthritis. A greater damage to the subchondral bone could be associated with more pain. Resumen: Objetivo: Determinar si las lesiones en el hueso subcondral en la artrosis de rodilla pueden condicionar el resultado del tratamiento con plasma rico en plaquetas (PRP) intraarticular. Material y métodos: Se revisó retrospectivamente a los pacientes con artrosis de rodilla tratados con PRP intraarticular sometidos previamente a una resonancia magnética (RM). Se evaluó la escala visual analógica (EVA) y las imágenes de resonancia mediante una adaptación de la escala WORMS graduando el daño al hueso subcondral (WORMSsc). Resultados: Se estudiaron 61 pacientes tratados con PRP intraarticular en 3 sesiones. Se obtuvo una mejoría en la escala EVA de 27,67 ± 13,13 puntos (p < 0,005). La puntuación de los ítems de la escala WORMSsc fue de 32 ± 18,5 puntos, no encontrándose correlación con la escala EVA. Se encontró una correlación moderada (r = 0,43; p < 0,005) entre la escala WORMSsc y la escala EVA pretratamiento. Conclusiones: No existe correlación entre el resultado clínico a las 12 semanas y el daño del hueso subcondral evaluado mediante RM en los pacientes con artrosis de rodilla tratados con PRP intraarticular. Un mayor daño del hueso subcondral podría estar asociado con mayor dolor.http://www.sciencedirect.com/science/article/pii/S1888441524002054ArtrosisRodillaPlasma rico en plaquetasResonancia magnética |
| spellingShingle | R. Escribano Rey [Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective study Revista Española de Cirugía Ortopédica y Traumatología Artrosis Rodilla Plasma rico en plaquetas Resonancia magnética |
| title | [Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective study |
| title_full | [Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective study |
| title_fullStr | [Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective study |
| title_full_unstemmed | [Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective study |
| title_short | [Translated article] Subchondral bone damage has no influence in 12-week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet-rich plasma: A retrospective study |
| title_sort | translated article subchondral bone damage has no influence in 12 week clinical outcome in patients with knee osteoarthritis treated with intraarticular platelet rich plasma a retrospective study |
| topic | Artrosis Rodilla Plasma rico en plaquetas Resonancia magnética |
| url | http://www.sciencedirect.com/science/article/pii/S1888441524002054 |
| work_keys_str_mv | AT rescribanorey translatedarticlesubchondralbonedamagehasnoinfluencein12weekclinicaloutcomeinpatientswithkneeosteoarthritistreatedwithintraarticularplateletrichplasmaaretrospectivestudy |