In Vivo Evolution of Lacticaseibacillus rhamnosus GG Leads to Prolonged Persistence in the Digestive Tract

In Vivo Evolution of Lacticaseibacillus rhamnosus GG Leads to Prolonged Persistence in the Digestive Tract

ABSTRACT This study explored in vivo evolution as a method to generate evolutionary clones of Lacticaseibacillus rhamnosus GG, a renowned probiotic organism found in many food supplements, with improved persistence in the intestinal tract. L. rhamnosus GG was autologously gavaged to mice and subsequ...

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Bibliographic Details
Main Authors: Alexander Mark, Lorenzo Tosi, Lamia Chkaiban, Raphaela Bento, Biju Parekkadan
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Food Bioengineering
Subjects:
intestinal drug delivery
microbiome
probiotics
strain engineering
Online Access:https://doi.org/10.1002/fbe2.70002
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