Hippo-YAP/TAZ-ROS signaling axis regulates metaflammation induced by SelenoM deficiency in high-fat diet-derived obesity

Hippo-YAP/TAZ-ROS signaling axis regulates metaflammation induced by SelenoM deficiency in high-fat diet-derived obesity

Introduction: Metabolic inflammation (metaflammation) in obesity is primarily initiated by proinflammatory macrophage infiltration into adipose tissue. SelenoM contributes to the modulation of antioxidative stress and inflammation in multiple pathological processes; however, its roles in metaflammat...

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Bibliographic Details
Main Authors: Jingzeng Cai, Jiaqiang Huang, Di Li, Xintong Zhang, Bendong Shi, Qiaohan Liu, Cheng Fang, Shiwen Xu, Ziwei Zhang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Advanced Research
Subjects:
SelenoM
Hippo-YAP/TAZ-ROS
Metaflammation
Oxidative stress
Obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224002297
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