Utility of a Modified Penlight‐Cover Test for Neurolocalization of Lesions Based on Visual Suppression of Nystagmus in Dogs and Cats With Vestibular Disease

ABSTRACT Background Humans with peripheral vestibular disorders can suppress nystagmus through visual fixation, a capability often compromised in those with central vestibular disorders. Bedside tests that exploit this difference can aid neurolocalization in humans. These tests remain unexplored in...

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Main Authors: Alice Chan, Gemma E. Longson, Edward Ives, Claire Turner, Paul Freeman, Stacey Brady, Ana Martinez Loro, Bruno Scalia, Susana Monforte Monteiro, Sara Formoso, Sam Khan, An E. Vanhaesebrouck
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Veterinary Internal Medicine
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Online Access:https://doi.org/10.1111/jvim.70182
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Summary:ABSTRACT Background Humans with peripheral vestibular disorders can suppress nystagmus through visual fixation, a capability often compromised in those with central vestibular disorders. Bedside tests that exploit this difference can aid neurolocalization in humans. These tests remain unexplored in veterinary medicine. Hypothesis Removal of visual input will reveal or enhance nystagmus in animals with peripheral vestibular disease, while animals with central vestibular disease would show little change. Animals Twenty‐one dogs and cats with peripheral vestibular lesions and 16 with central vestibular lesions. Diagnosis was confirmed by MRI. Methods A prospective study was conducted using a modified penlight‐cover test. Because animals cannot be easily instructed to fixate on a visual target, removal of visual input was used as a substitute for eliminating visual fixation, based on the assumption that visual fixation also occurs spontaneously. A 0.5‐W LED penlight was shined into one eye while covering the other to eliminate visual input. Nystagmus beat frequency (BF) and subjective evaluation of slow phase velocity (SPV) were recorded before and during penlight application. Results In animals with peripheral lesions, BF increased in 33% and SPV in 24% of cases after removal of visual input. Among those with central lesions, only one of 16 showed an increase in BF, and none exhibited an increase in SPV. Conclusions When used alongside the neurological examination, the modified penlight‐cover test, could raise suspicion of a peripheral vestibular lesion if it reveals increased BF or SPV.
ISSN:0891-6640
1939-1676