Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches

Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches

Unlocking the potential of broadly reactive coronavirus monoclonal antibodies (mAbs) and their derivatives offers a transformative therapeutic avenue against severe COVID-19, especially crucial for safeguarding high-risk populations. Novel mAb-based immunotherapies may help address the reduced effic...

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Bibliographic Details
Main Authors: Daouda Abba Moussa, Mario Vazquez, Christine Chable-Bessia, Vincent Roux-Portalez, Elia Tamagnini, Mattia Pedotti, Luca Simonelli, Giang Ngo, Manon Souchard, Sebastien Lyonnais, Myriam Chentouf, Nathalie Gros, Soledad Marsile-Medun, Heiko Dinter, Martine Pugnière, Pierre Martineau, Luca Varani, Manel Juan, Hugo Calderon, Mar Naranjo-Gomez, Mireia Pelegrin
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
Non-neutralizing antibodies
infected cell-targeting
SARS-CoV-2
antibody-based therapy
cell therapy
CAR-T cells
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2432345
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