Diagnostic Characteristics of Familial Hypercholesterolemia in Children

Familial hypercholesterolemia is autosomal dominant hereditary disorder developing in in humans since birth and it is characterized by low-density lipoproteins concentration increase in blood. Lack of timely diagnostics and therapy for familial hypercholesterolemia is associated with early developme...

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Main Authors: Dinara I. Sadykova, Liliia F. Galimova, Eugenia S. Slastnikova
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2020-06-01
Series:Педиатрическая фармакология
Subjects:
Online Access:https://www.pedpharma.ru/jour/article/view/1836
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author Dinara I. Sadykova
Liliia F. Galimova
Eugenia S. Slastnikova
author_facet Dinara I. Sadykova
Liliia F. Galimova
Eugenia S. Slastnikova
author_sort Dinara I. Sadykova
collection DOAJ
description Familial hypercholesterolemia is autosomal dominant hereditary disorder developing in in humans since birth and it is characterized by low-density lipoproteins concentration increase in blood. Lack of timely diagnostics and therapy for familial hypercholesterolemia is associated with early development of atherosclerosis, cardiovascular pathology and mortality in first 30–40 days of life. Despite the fact that the optimal period for revealing of disease is childhood, diagnostics of the disease has extremely low quality among children. The article presents screening methods and criteria of familial hypercholesterolemia diagnostics among children.
format Article
id doaj-art-adb1e62325bd4b07985477cb71769451
institution DOAJ
issn 1727-5776
2500-3089
language Russian
publishDate 2020-06-01
publisher Union of pediatricians of Russia
record_format Article
series Педиатрическая фармакология
spelling doaj-art-adb1e62325bd4b07985477cb717694512025-08-20T03:19:42ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892020-06-0117212412810.15690/pf.v17i2.20981709Diagnostic Characteristics of Familial Hypercholesterolemia in ChildrenDinara I. Sadykova0Liliia F. Galimova1Eugenia S. Slastnikova2Kazan State Medical UniversityChildren’s Republican Clinical Hospital of the Ministry of Health of the Republic of TatarstanKazan State Medical University; Children’s Republican Clinical Hospital of the Ministry of Health of the Republic of TatarstanFamilial hypercholesterolemia is autosomal dominant hereditary disorder developing in in humans since birth and it is characterized by low-density lipoproteins concentration increase in blood. Lack of timely diagnostics and therapy for familial hypercholesterolemia is associated with early development of atherosclerosis, cardiovascular pathology and mortality in first 30–40 days of life. Despite the fact that the optimal period for revealing of disease is childhood, diagnostics of the disease has extremely low quality among children. The article presents screening methods and criteria of familial hypercholesterolemia diagnostics among children.https://www.pedpharma.ru/jour/article/view/1836childrenfamilial hypercholesterolemialow-density lipoproteinsscreeningcriteria
spellingShingle Dinara I. Sadykova
Liliia F. Galimova
Eugenia S. Slastnikova
Diagnostic Characteristics of Familial Hypercholesterolemia in Children
Педиатрическая фармакология
children
familial hypercholesterolemia
low-density lipoproteins
screening
criteria
title Diagnostic Characteristics of Familial Hypercholesterolemia in Children
title_full Diagnostic Characteristics of Familial Hypercholesterolemia in Children
title_fullStr Diagnostic Characteristics of Familial Hypercholesterolemia in Children
title_full_unstemmed Diagnostic Characteristics of Familial Hypercholesterolemia in Children
title_short Diagnostic Characteristics of Familial Hypercholesterolemia in Children
title_sort diagnostic characteristics of familial hypercholesterolemia in children
topic children
familial hypercholesterolemia
low-density lipoproteins
screening
criteria
url https://www.pedpharma.ru/jour/article/view/1836
work_keys_str_mv AT dinaraisadykova diagnosticcharacteristicsoffamilialhypercholesterolemiainchildren
AT liliiafgalimova diagnosticcharacteristicsoffamilialhypercholesterolemiainchildren
AT eugeniasslastnikova diagnosticcharacteristicsoffamilialhypercholesterolemiainchildren