Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib
Abstract Both bullous pemphigoid and mucous membrane pemphigoid are autoimmune bullous diseases that can be challenging to treat in individual cases. Janus kinase inhibitors have shown efficacy in several autoimmune and inflammatory diseases, although these drugs are not yet widely used in autoimmun...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-12-01
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| Series: | JEADV Clinical Practice |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jvc2.511 |
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| _version_ | 1850059314470846464 |
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| author | Tamás Malkovics Orsolya N. Horváth Miklós Sárdy |
| author_facet | Tamás Malkovics Orsolya N. Horváth Miklós Sárdy |
| author_sort | Tamás Malkovics |
| collection | DOAJ |
| description | Abstract Both bullous pemphigoid and mucous membrane pemphigoid are autoimmune bullous diseases that can be challenging to treat in individual cases. Janus kinase inhibitors have shown efficacy in several autoimmune and inflammatory diseases, although these drugs are not yet widely used in autoimmune bullous diseases. We report two recalcitrant cases of pemphigoid with mucous membrane involvement which were successfully treated with the JAK 1/2 inhibitor baricitinib after all other feasible therapeutic options had been exhausted. |
| format | Article |
| id | doaj-art-ada883b300234df9a6ea2fc6d5d997a8 |
| institution | DOAJ |
| issn | 2768-6566 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | JEADV Clinical Practice |
| spelling | doaj-art-ada883b300234df9a6ea2fc6d5d997a82025-08-20T02:50:55ZengWileyJEADV Clinical Practice2768-65662024-12-01351656165910.1002/jvc2.511Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinibTamás Malkovics0Orsolya N. Horváth1Miklós Sárdy2Department of Dermatology, Venereology, and Dermatooncology Semmelweis University Budapest HungaryDepartment of Dermatology and Allergy, University Hospital LMU Munich Munich GermanyDepartment of Dermatology, Venereology, and Dermatooncology Semmelweis University Budapest HungaryAbstract Both bullous pemphigoid and mucous membrane pemphigoid are autoimmune bullous diseases that can be challenging to treat in individual cases. Janus kinase inhibitors have shown efficacy in several autoimmune and inflammatory diseases, although these drugs are not yet widely used in autoimmune bullous diseases. We report two recalcitrant cases of pemphigoid with mucous membrane involvement which were successfully treated with the JAK 1/2 inhibitor baricitinib after all other feasible therapeutic options had been exhausted.https://doi.org/10.1002/jvc2.511baricitinibbullous pemphigoidJanus kinase inhibitormucous membrane pemphigoid |
| spellingShingle | Tamás Malkovics Orsolya N. Horváth Miklós Sárdy Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib JEADV Clinical Practice baricitinib bullous pemphigoid Janus kinase inhibitor mucous membrane pemphigoid |
| title | Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib |
| title_full | Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib |
| title_fullStr | Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib |
| title_full_unstemmed | Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib |
| title_short | Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib |
| title_sort | two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib |
| topic | baricitinib bullous pemphigoid Janus kinase inhibitor mucous membrane pemphigoid |
| url | https://doi.org/10.1002/jvc2.511 |
| work_keys_str_mv | AT tamasmalkovics twopemphigoidcaseswithmucousmembraneinvolvementsuccessfullytreatedwithbaricitinib AT orsolyanhorvath twopemphigoidcaseswithmucousmembraneinvolvementsuccessfullytreatedwithbaricitinib AT miklossardy twopemphigoidcaseswithmucousmembraneinvolvementsuccessfullytreatedwithbaricitinib |